Humanising the mouse genome piece by piece (Q64097689)

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Humanising the mouse genome piece by piece (English)

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Elizabeth M. C. Fisher

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Thomas J. Cunningham

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Fei Zhu

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Remya R Nair

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23 April 2019

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Nature Communications

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Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Genomically humanized mice: technologies and promises

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mouse Models of C9orf72 Hexanucleotide Repeat Expansion in Amyotrophic Lateral Sclerosis/ Frontotemporal Dementia

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The state-of-play and future of antibody therapeutics.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Single App knock-in mouse models of Alzheimer's disease.

1 reference

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7 January 2021

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A genetic determinant of the striatal dopamine response to alcohol in men

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Apo E structure determines VLDL clearance and atherosclerosis risk in mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized mouse model supports development, function, and tissue residency of human natural killer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Efficient differentiation and function of human macrophages in humanized CSF-1 mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Development and function of human innate immune cells in a humanized mouse model

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Generation and utility of genetically humanized mouse models.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Dissecting Alzheimer disease in Down syndrome using mouse models

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Chromosome looping at the human alpha-globin locus is mediated via the major upstream regulatory element (HS -40).

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A BACwards glance at neurodegeneration: molecular insights into disease from LRRK2, SNCA and MAPT BAC-transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The long-range interaction landscape of gene promoters

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Species-specific transcription in mice carrying human chromosome 21

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Universal Alternative Splicing of Noncoding Exons

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Initial sequencing and comparative analysis of the mouse genome

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Prevalence, incidence and carrier frequency of 5q-linked spinal muscular atrophy - a literature review.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mouse models of SMA: tools for disease characterization and therapeutic development

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Replacing the Mouse Androgen Receptor with Human Alleles Demonstrates Glutamine Tract Length-Dependent Effects on Physiology and Tumorigenesis in Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Neuromuscular junctions are pathological but not denervated in two mouse models of spinal bulbar muscular atrophy.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Abnormalities of germ cell maturation and sertoli cell cytoskeleton in androgen receptor 113 CAG knock-in mice reveal toxic effects of the mutant protein

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized Mouse Model of Cooley's Anemia

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Correction of sickle cell disease by homologous recombination in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Preclinical transfusion-dependent humanized mouse model of beta thalassemia major.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized mouse models of Cooley's anemia: correct fetal-to-adult hemoglobin switching, disease onset, and disease pathology

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Humanized prion protein knock-in by Cre-induced site-specific recombination in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Latent regulatory potential of human-specific repetitive elements

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

In vivo modeling of human neuron dynamics and Down syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

New developments in RAN translation: insights from multiple diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Recent advances in understanding transcription termination by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Transcription Termination: Variations on Common Themes

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Classification of Transcription Boundary-Associated RNAs (TBARs) in Animals and Plants.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Alternative 3' UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Codon optimality, bias and usage in translation and mRNA decay

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Why are some human disease-associated mutations fixed in mice?

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Identification of cis-suppression of human disease mutations by comparative genomics

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Mouse Models of Human GWAS Hits for Obesity and Diabetes in the Post Genomic Era: Time for Reevaluation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

The contribution of homology arms to nuclease-assisted genome engineering.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

CRISPR off-target analysis in genetically engineered rats and mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-019-09716-7

7 January 2021

A common human beta globin splicing mutation modeled in mice

1 reference

12 December 2020

Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

1 reference

12 December 2020

Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model

1 reference

12 December 2020

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis

1 reference

12 December 2020

10.1038/S41467-019-09716-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31015419%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31015419%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

31015419

1 reference