The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity (Q63359855)

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5 December 2019

title

The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity (English)

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5 December 2019

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4

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5 December 2019

author name string

Jeanine de Keyzer

series ordinal

1

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5 December 2019

Chris van der Does

series ordinal

2

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5 December 2019

Jelto Swaving

series ordinal

3

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5 December 2019

language of work or name

English

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publication date

1 January 2002

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5 December 2019

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5 December 2019

volume

510

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5 December 2019

issue

1-2

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5 December 2019

page(s)

17-21

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The structural basis of protein targeting and translocation in bacteria.

5 December 2019

cites work

1 reference

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The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

21 January 2018

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ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocase

21 January 2018

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SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion.

21 January 2018

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The catalytic cycle of the Escherichia coli SecA ATPase comprises two distinct preprotein translocation events

21 January 2018

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Specific recognition of the leader region of precursor proteins is required for the activation of translocation ATPase of Escherichia coli

21 January 2018

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The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins

21 January 2018

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Novel secA alleles improve export of maltose-binding protein synthesized with a defective signal peptide

21 January 2018

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New suppressors of signal-sequence mutations, prlG, are linked tightly to the secE gene of Escherichia coli.

21 January 2018

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prl mutations in the Escherichia coli secG gene

21 January 2018

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PrlA and PrlG suppressors reduce the requirement for signal sequence recognition

21 January 2018

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Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA

21 January 2018

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Suppressor mutations that restore export of a protein with a defective signal sequence

21 January 2018

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PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation

21 January 2018

1 reference

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prlA suppressors in Escherichia coli relieve the proton electrochemical gradient dependency of translocation of wild-type precursors

21 January 2018

1 reference

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Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation

21 January 2018

1 reference

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The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits

21 January 2018

1 reference

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Distinct mutation sites in prlA suppressor mutant strains of Escherichia coli respond either to suppression of signal peptide mutations or to blockage of staphylokinase processing

21 January 2018

1 reference

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SecYEG assembles into a tetramer to form the active protein translocation channel

21 January 2018

1 reference

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Cysteine-Directed Cross-Linking Demonstrates That Helix 3 of SecE Is Close to Helix 2 of SecY and Helix 3 of a Neighboring SecE†

21 January 2018

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Effect of OmpA signal peptide mutations on OmpA secretion, synthesis, and assembly

21 January 2018

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A Single Amino Acid Substitution in SecY Stabilizes the Interaction with SecA

21 January 2018

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The sec and prl genes of Escherichia coli

21 January 2018

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Interaction between SecA and SecYEG in Micellar Solution and Formation of the Membrane-Inserted State†

21 January 2018

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Reconstitution of a protein translocation system containing purified SecY, SecE, and SecA from Escherichia coli

21 January 2018

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Different PrlA proteins increase the efficiency of periplasmic production of human interleukin-6 in Escherichia coli.

21 January 2018

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Mapping the sites of interaction between SecY and SecE by cysteine scanning mutagenesis.

21 January 2018

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Projection structure and oligomeric properties of a bacterial core protein translocase

21 January 2018

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PrlA suppressor mutations cluster in regions corresponding to three distinct topological domains

21 January 2018

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SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA.

7 January 2021

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A signal sequence is not required for protein export in prlA mutants of Escherichia coli

7 January 2021

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A novel membrane protein involved in protein translocation across the cytoplasmic membrane of Escherichia coli.

7 January 2021

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10.1016/S0014-5793(01)03213-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11755523%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference