A Single Amino Acid Change Converts an Inhibitory Transcription Factor into an Activator (Q60617941)

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16 October 2019

title

A single amino acid change converts an inhibitory transcription factor into an activator (English)

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16 October 2019

1

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16 October 2019

author name string

P J Morris

series ordinal

2

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16 October 2019

D S Latchman

series ordinal

3

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16 October 2019

language of work or name

English

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publication date

1 May 1996

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Journal of Biological Chemistry

16 October 2019

published in

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16 October 2019

volume

271

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16 October 2019

issue

20

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16 October 2019

page(s)

11631-11633

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POU domain transcription factors

16 October 2019

cites work

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POU-domain proteins: structure and function of developmental regulators

21 January 2018

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A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons

21 January 2018

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The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

21 January 2018

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Expression of a large family of POU-domain regulatory genes in mammalian brain development

21 January 2018

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Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a

21 January 2018

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Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

21 January 2018

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Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs

21 January 2018

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A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells

21 January 2018

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Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid

21 January 2018

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A novel Brn3-like POU transcription factor expressed in subsets of rat sensory and spinal cord neurons.

21 January 2018

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Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors

21 January 2018

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The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements

21 January 2018

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The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

21 January 2018

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Novel cell lines display properties of nociceptive sensory neurons.

21 January 2018

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Intracellular redistribution of neuropeptides and secretory proteins during differentiation of neuronal cell lines

21 January 2018

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The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site

21 January 2018

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Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein

21 January 2018

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Polyoma transformation of hamster cell clones—an investigation of genetic factors affecting cell competence

21 January 2018

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A procedure to standardize CAT reporter gene assay

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

21 January 2018

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Recognition of the surface of a homeo domain protein

21 January 2018

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A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.20.11631

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8662774%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

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