Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats (Q60046979)

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English	Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats	No description defined

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scholarly article

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Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats (English)

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author name string

Congcong Guo

1

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Yun Li

2

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Rui Zhang

3

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Yaqin Zhang

4

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Junyu Zhao

5

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Jinming Yao

6

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Jie Sun

7

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Jianjun Dong

8

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Lin Liao

9

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language of work or name

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publication date

2018

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Frontiers in Pharmacology

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9

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1433

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copyright license

Creative Commons Attribution 4.0 International

4 December 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

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The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of tubular epithelial cells in glycogen nephrosis during diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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The genetic association database

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https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that inhibition of tubular cell apoptosis protects against renal damage and development of fibrosis following ureteric obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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Reactome: a knowledge base of biologic pathways and processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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DrugBank: a knowledgebase for drugs, drug actions and drug targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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Inhibition of MMP2/MMP9 after spinal cord trauma reduces apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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STRING 8--a global view on proteins and their functional interactions in 630 organisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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Salidroside, the main active compound of Rhodiola plants, inhibits high glucose-induced mesangial cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Transglutaminase inhibition ameliorates experimental diabetic nephropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Bax activation by Bim?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathologic classification of diabetic nephropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Dual regulation of hepatocyte apoptosis by reactive oxygen species: Increases in transcriptional expression and decreases in proteasomal degradation of BimEL.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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HIT: linking herbal active ingredients to targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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The Therapeutic Target Database: an internet resource for the primary targets of approved, clinical trial and experimental drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Bim: Guardian of Tissue Homeostasis and Critical Regulator of the Immune System, Tumorigenesis and Bone Biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Genetic network analyzer: a tool for the qualitative modeling and simulation of bacterial regulatory networks.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Bcl-2-modifying factor induces renal proximal tubular cell apoptosis in diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Neutrophil gelatinase-associated lipocalin (NGAL) may play a protective role against rats ischemia/reperfusion renal injury via inhibiting tubular epithelial cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ChemMapper: a versatile web server for exploring pharmacology and chemical structure association based on molecular 3D similarity method.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ethanol extract of Rhodiola rosea on the early nephropathy in type 2 diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Rap1 ameliorates renal tubular injury in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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STAT1-mediated Bim expression promotes the apoptosis of retinal pericytes under high glucose conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.

1 reference

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12 December 2020

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Protein-protein interaction network analyses for elucidating the roles of LOXL2-delta72 in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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SwissTargetPrediction: a web server for target prediction of bioactive small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Salidroside alleviates paraquat-induced rat acute lung injury by repressing TGF-β1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Protective activity of salidroside against ethanol-induced gastric ulcer via the MAPK/NF-κB pathway in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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The cardioprotective effect of salidroside against myocardial ischemia reperfusion injury in rats by inhibiting apoptosis and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Communication from Tubular Epithelial Cells to Podocytes through Sirt1 and Nicotinic Acid Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of salidroside against bone loss via hypoxia-inducible factor-1α pathway-induced angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Trends in Chronic Kidney Disease in China

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Comparative Study on the Protective Effects of Salidroside and Hypoxic Preconditioning for Attenuating Anoxia-Induced Apoptosis in Pheochromocytoma (PC12) Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium Dobesilate Prevents Diabetic Kidney Disease by Decreasing Bim and Inhibiting Apoptosis of Renal Proximal Tubular Epithelial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

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Proximal Tubulopathy: Prime Mover and Key Therapeutic Target in Diabetic Kidney Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Searching Online Mendelian Inheritance in Man (OMIM): A Knowledgebase of Human Genes and Genetic Phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huangqi Decoction Ameliorates Streptozotocin-Induced Rat Diabetic Nephropathy through Antioxidant and Regulation of the TGF-β/MAPK/PPAR-γ Signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 mediates salidroside-elicited protective effects against MPP+ -induced apoptosis and oxidative stress in SH-SY5Y cells: involvement in suppressing MAPK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-25 inhibits high glucose-induced apoptosis in renal tubular epithelial cells via PTEN/AKT pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salidroside alleviates high glucose-induced oxidative stress and extracellular matrix accumulation in rat glomerular mesangial cells by the TXNIP-NLRP3 inflammasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue expression of tubular injury markers is associated with renal function decline in diabetic nephropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing the Protein-Protein Interaction Network of Proteins Causing Maturity Onset Diabetes of the Young

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil Gelatinase-associated Lipocalin: As a Predictor of Early Diabetic Nephropathy in Type 2 Diabetes Mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

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The Comparative Toxicogenomics Database: update 2019

1 reference

https://pubmed.ncbi.nlm.nih.gov/30564128

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FPHAR.2018.01433

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