Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain (Q58478774)

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6 December 2019

title

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain (English)

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6 December 2019

1

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6 December 2019

James P Di Santo

5

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6 December 2019

author name string

M P Blundell

2

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6 December 2019

L Lopes

3

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6 December 2019

C Kinnon

4

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A J Thrasher

6

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language of work or name

English

0 references

publication date

1 November 1998

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British Journal of Haematology

6 December 2019

published in

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volume

103

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issue

2

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page(s)

335-342

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Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.

6 December 2019

cites work

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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Evidence of functional lymphocytes in some (leaky) scid mice

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

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Transplantation of Normal and Leukemic Human Bone Marrow into Immune-Deficient Mice: Development of Animal Models for Human Hematopoiesis

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Cytokines: shared receptors, distinct functions.

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Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection

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Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice

21 January 2018

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Role of murine NK cells and their receptors in hybrid resistance

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Human Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes home preferentially to and induce selective regressions of autologous EBV-induced B cell lymphoproliferations in xenografted C.B-17 scid/scid mice

21 January 2018

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Lineage relationships and differentiation of natural killer (NK) T cells: intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 molecules

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Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.

21 January 2018

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The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

21 January 2018

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Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

21 January 2018

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RAG-1-deficient mice have no mature B and T lymphocytes

21 January 2018

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Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions

21 January 2018

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Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized

21 January 2018

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The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis

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Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

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RAG mutations in human B cell-negative SCID.

21 January 2018

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

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High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1.

21 January 2018

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The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

21 January 2018

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Human mature T cells that are anergic in vivo prevail in SCID mice reconstituted with human peripheral blood

21 January 2018

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The human immune system in hu-PBL-SCID mice

21 January 2018

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Transfer of a functional human immune system to mice with severe combined immunodeficiency

21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9827902%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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