The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor (Q58114531)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

8 February 2021

The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

0 references

1 reference

8 February 2021

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Jonathan Jaoude

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Imad Shureiqi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

author name string

Yi Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Xiangsheng Zuo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Daoyan Wei

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

0 references

publication date

26 October 2018

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

8 February 2021

International Journal of Molecular Sciences

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

8 February 2021

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

1 May 2020

copyright license

1 reference

8 February 2021

0 references

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

1 reference

12 December 2020

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

1 reference

12 December 2020

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

1 reference

12 December 2020

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

1 reference

12 December 2020

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

1 reference

12 December 2020

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer

1 reference

12 December 2020

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

1 reference

12 December 2020

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

1 reference

12 December 2020

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

1 reference

12 December 2020

Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription

1 reference

12 December 2020

Emerging roles of PPARs in inflammation and immunity

1 reference

12 December 2020

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

1 reference

12 December 2020

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

1 reference

12 December 2020

Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle

1 reference

12 December 2020

The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells

1 reference

12 December 2020

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

1 reference

12 December 2020

Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

1 reference

12 December 2020

Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses.

1 reference

12 December 2020

Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta

1 reference

12 December 2020

Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand

1 reference

12 December 2020

Mechanisms for the prevention of gastrointestinal cancer: the role of prostaglandin E2.

1 reference

12 December 2020

PPARdelta regulates glucose metabolism and insulin sensitivity

1 reference

12 December 2020

Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta

1 reference

12 December 2020

Ligand-activated PPARbeta efficiently represses the induction of LXR-dependent promoter activity through competition with RXR

1 reference

12 December 2020

Expression of PPARdelta in multistage carcinogenesis of the colorectum: implications of malignant cancer morphology

1 reference

12 December 2020

Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression

1 reference

12 December 2020

Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells

1 reference

12 December 2020

Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

1 reference

12 December 2020

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

1 reference

12 December 2020

Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice

1 reference

12 December 2020

Transcriptional network governing the angiogenic switch in human pancreatic cancer

1 reference

12 December 2020

PPAR delta as a therapeutic target in metabolic disease.

1 reference

12 December 2020

Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer

1 reference

12 December 2020

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

1 reference

12 December 2020

Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis

1 reference

12 December 2020

PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance

1 reference

12 December 2020

15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist

1 reference

12 December 2020

PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction

1 reference

12 December 2020

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions

1 reference

12 December 2020

Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

1 reference

12 December 2020

Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo

1 reference

12 December 2020

Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis

1 reference

12 December 2020

Inflammation and colon cancer

1 reference

12 December 2020

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity

1 reference

12 December 2020

Coactivators in PPAR-Regulated Gene Expression

1 reference

12 December 2020

The Expression of Both Peroxisome Proliferator-Activated Receptor Delta and Cyclooxygenase-2 in Tissues Is Associated with Poor Prognosis in Colorectal Cancer Patients

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptor delta inhibits streptozotocin-induced diabetic nephropathy through anti-inflammatory mechanisms in mice

1 reference

12 December 2020

Hallmarks of Cancer: The Next Generation

1 reference

12 December 2020

PPARs and Lipid Ligands in Inflammation and Metabolism

1 reference

12 December 2020

Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies

1 reference

12 December 2020

The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases

1 reference

12 December 2020

Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding

1 reference

12 December 2020

Peroxisome proliferator-activated receptor δ agonist attenuates hepatic steatosis by anti-inflammatory mechanism

1 reference

12 December 2020

A metabolic prosurvival role for PML in breast cancer.

1 reference

12 December 2020

Targeting peroxisome proliferator-activated receptor-β/δ in colon cancer: how to aim?

1 reference

12 December 2020

PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

1 reference

12 December 2020

PPARβ/δ governs Wnt signaling and bone turnover

1 reference

12 December 2020

PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

1 reference

12 December 2020

PPARδ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation

1 reference

12 December 2020

Mesenchymal stromal cells: sensors and switchers of inflammation

1 reference

12 December 2020

Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells

1 reference

12 December 2020

Regulation of energy metabolism by long-chain fatty acids

1 reference

12 December 2020

New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease

1 reference

12 December 2020

Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-δ/β overexpression.

1 reference

12 December 2020

Structural Basis for Ligand Regulation of the Fatty Acid-binding Protein 5, Peroxisome Proliferator-activated Receptor / (FABP5-PPAR / ) Signaling Pathway

1 reference

12 December 2020

Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth

1 reference

12 December 2020

Tumor-associated macrophages contribute to tumor progression in ovarian cancer.

1 reference

12 December 2020

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

1 reference

12 December 2020

Ligand-activated PPARδ modulates the migration and invasion of melanoma cells by regulating Snail expression.

1 reference

12 December 2020

15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway

1 reference

12 December 2020

The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

1 reference

12 December 2020

PPARδ and PGE2 signaling pathways communicate and connect inflammation to colorectal cancer

1 reference

12 December 2020

Establishing the Role of PPARβ/δ in Carcinogenesis

1 reference

12 December 2020

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

1 reference

12 December 2020

PPARβ/δ directs the therapeutic potential of mesenchymal stem cells in arthritis.

1 reference

12 December 2020

A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome

1 reference

12 December 2020

PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditions

1 reference

12 December 2020

A guide to immunometabolism for immunologists.

1 reference

12 December 2020

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.

1 reference

12 December 2020

PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice.

1 reference

12 December 2020

PPARβ/δ in human cancer

1 reference

12 December 2020

PPARβ in macrophages and atherosclerosis

1 reference

12 December 2020

PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions

1 reference

12 December 2020

Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome

1 reference

12 December 2020

Metastasis regulation by PPARD expression in cancer cells.

1 reference

12 December 2020

Rationally designed PPARδ-specific agonists and their therapeutic potential for metabolic syndrome

1 reference

12 December 2020

Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

1 reference

12 December 2020

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

1 reference

12 December 2020

PPARδ Promotes Running Endurance by Preserving Glucose

1 reference

12 December 2020

1 reference

12 December 2020

PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth.

1 reference

12 December 2020

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

1 reference

12 December 2020

Insights into the Role of PPARβ/δ in NAFLD

1 reference

12 December 2020

Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS19113339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373124%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30373124

1 reference