Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking (Q58105661)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Xin Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

11

C David Allis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

author name string

Xiao-Meng Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Yixiang Jiang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Zheng Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Yiwen Cui

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Ka Yi Fung

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Stan H E van der Beelen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Gaofei Tian

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Liling Wan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Xiaobing Shi

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Yuanyuan Li

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Xiang David Li

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

0 references

publication date

29 October 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

page(s)

1140-1149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6503841/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Chromatin modifications and their function

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

SnapShot: Histone-modifying enzymes

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Readout of epigenetic modifications

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Perceiving the epigenetic landscape through histone readers.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Signals and Combinatorial Functions of Histone Modifications

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Covalent modifications of histones during development and disease pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Epigenetic protein families: a new frontier for drug discovery

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Chromatin proteins and modifications as drug targets

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Chemical probes for histone-modifying enzymes

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Writers and readers of histone acetylation: structure, mechanism, and inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Targeting bromodomains: epigenetic readers of lysine acetylation

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

A chemical probe toolbox for dissecting the cancer epigenome

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

YEATS Domain-A Histone Acylation Reader in Health and Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

YEATS domain proteins: a diverse family with many links to chromatin modification and transcription.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The Taf14 YEATS domain is a reader of histone crotonylation

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

YEATS2 is a selective histone crotonylation reader.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Transcription control by the ENL YEATS domain in acute leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

YEATS domain: Linking histone crotonylation to gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Enzyme inhibitor discovery by activity-based protein profiling

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Approach to profile proteins that recognize post-translationally modified histone "tails".

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Developing diazirine-based chemical probes to identify histone modification 'readers' and 'erasers'.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The cellular thermal shift assay for evaluating drug target interactions in cells

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

BET bromodomain inhibitors in leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Chromatin as an expansive canvas for chemical biology

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Probing the epigenome

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

pi-Stacking interactions. Alive and well in proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

A feature-based approach to modeling protein-protein interaction hot spots.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Crosstalk among Histone Modifications

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The Language of Histone Crosstalk

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Functional interdependence of BRD4 and DOT1L in MLL leukemia

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Inside Job: Methods for Delivering Proteins to the Interior of Mammalian Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

The super elongation complex (SEC) family in transcriptional control

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Quantitative chemical proteomics approach to identify post-translational modification-mediated protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Molecular replacement with MOLREP

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1038%2FS41589-018-0144-Y

7 January 2021

10.1038/S41589-018-0144-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30374167%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30374167

1 reference