Fluorine in Peptide Design and Protein Engineering (Q57983889)

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Protease-catalyzed peptide synthesis for the site-specific incorporation of alpha-fluoroalkyl amino acids into peptides

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Peptide synthesis using unprotected peptides through orthogonal coupling methods

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Methods and strategies of peptide ligation

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Orthogonal ligation strategies for peptide and protein

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Expressed protein ligation. Method and applications

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Expressed protein ligation: a general method for protein engineering

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

An expanded eukaryotic genetic code

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

An expanded genetic code with a functional quadruplet codon

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Site-specific incorporation of unnatural amino acids into proteins.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Organic fluorine: odd man out.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Elucidation of solvent exposure, side-chain reactivity, and steric demands of the trifluoromethionine residue in a recombinant protein.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Hydrogen bridges in crystal engineering: interactions without borders

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Organic Fluorine Hardly Ever Accepts Hydrogen Bonds

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Hydrogen bonding interactions of covalently bonded fluorine atoms: from crystallographic data to a new angular function in the GRID force field

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Selectivity of DNA Replication: The Importance of Base-Pair Geometry over Hydrogen Bonding

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A thymidine triphosphate shape analog lacking Watson–Crick pairing ability is replicated with high sequence selectivity

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Solution Structure of a Nonpolar, Non-Hydrogen-Bonded Base Pair Surrogate in DNA

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

C-F...H-C hydrogen bonds in ribonucleic acids

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Observation of intramolecular C-H..F-C contacts in non-metallocene polyolefin catalysts: model for weak attractive interactions between polymer chain and noninnocent ligand

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

The C-F small middle dot small middle dot small middle dotH-C "Anti-Hydrogen Bond" in the Gas Phase: Microwave Structure of the Difluoromethane Dimer

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Some influences of fluorine in bioorganic chemistry

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Synthesis of 2'-aminoalkyl-substituted fluorinated nucleobases and their influence on the kinetic properties of hammerhead ribozymes

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Atropisomerism, biphenyls, and fluorine: a comparison of rotational barriers and twist angles.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorinated carbonyl and olefinic compounds: basic character and asymmetric catalytic reactions

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Alternative translations of a single RNA message: an identity switch of (2S,3R)-4,4,4-trifluorovaline between valine and isoleucine codons

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

The polar hydrophobicity of fluorinated compounds.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorine in medicinal chemistry

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Metabolism of fluorine-containing drugs

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorine substitution can block CYP3A4 metabolism-dependent inhibition: identification of (S)-N-[1-(4-fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an orally bioavailable KCNQ2 opener devoid of CYP3A4 metabolism-dependent in

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Halogenation of drugs enhances membrane binding and permeation

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Increasing Binding Constants of Ligands to Carbonic Anhydrase by Using "Greasy Tails"

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Use of fluorine in the medicinal chemistry and chemical biology of bioactive compounds--a case study on fluorinated taxane anticancer agents

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Urea-dependent unfolding of murine adenosine deaminase: sequential destabilization as measured by 19F NMR.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Real-time and equilibrium (19)F-NMR studies reveal the role of domain-domain interactions in the folding of the chaperone PapD.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Side chain accessibility and dynamics in the molten globule state of alpha-lactalbumin: a (19)F-NMR study

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Solid-state 19F-NMR analysis of 19F-labeled tryptophan in gramicidin A in oriented membranes

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Influence of proline position upon the ion channel activity of alamethicin

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Alamethicin: A Peptide Model for Voltage Gating and Protein-Membrane Interactions

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Oxygen as a paramagnetic probe of membrane protein structure by cysteine mutagenesis and (19)F NMR spectroscopy.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Incorporation of trifluoromethionine into a phage lysozyme: implications and a new marker for use in protein 19F NMR.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Design of a functional protein for molecular recognition: specificity of ligand binding in a metal-assembled protein cavity probed by 19f NMR.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Human factor Xa bound amidine inhibitor conformation by double rotational-echo double resonance nuclear magnetic resonance and molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorinated tracers for imaging cancer with positron emission tomography

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Peptide modification by introduction of?-trifluoromethyl substituted amino acids

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A New Strategy for the Synthesis of α-Difluoromethyl-Substituted α-Hydroxy and α-Amino Acids

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

New developments in the chemo-enzymatic production of amino acids

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Biochemistry: biosynthesis of an organofluorine molecule

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Cell-free biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Crystal structure and mechanism of a bacterial fluorinating enzyme

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Unnatural amino acid mutagenesis: a precise tool for probing protein structure and function.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Enzymes for the resolution of alpha-tertiary-substituted carboxylic acid esters

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Kinetic studies of carboxypeptidase Y. III. Action on ester, amide, and anilide substrates and the effects of some environmental factors

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

2.8-A structure of yeast serine carboxypeptidase

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Protease-catalyzed peptide synthesis using inverse substrates: the influence of reaction conditions on the trypsin acyl transfer efficiency

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Protease-catalyzed peptide synthesis using inverse substrates: the synthesis of Pro-Xaa-bonds by trypsin

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Protease-catalyzed hydrolysis of substrate mimetics (inverse substrates): A new approach reveals a new mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Protease-catalyzed fragment condensation via substrate mimetic strategy: a useful combination of solid-phase peptide synthesis with enzymatic methods

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Semisynthesis of Ht31(493--515): involvement of PKA-anchoring proteins in the regulation of the cAMP-dependent chloride current in heart cells

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Substrate mimetics and freezing strategy: a useful combination that broadens the scope of proteases for synthesis

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Methyl- and (Trifluoromethyl)alkene Peptide Isosteres: Synthesis and Evaluation of Their Potential as beta-Turn Promoters and Peptide Mimetics

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A (4R)- or a (4S)-fluoroproline residue in position Xaa of the (Xaa-Yaa-Gly) collagen repeat severely affects triple-helix formation.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorinated amino acids in protein design and engineering

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

phi-Values beyond the ribosomally encoded amino acids: kinetic and thermodynamic consequences of incorporating trifluoromethyl amino acids in a globular protein

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Self-association and membrane-binding behavior of melittins containing trifluoroleucine

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Incorporation of trifluoroisoleucine into proteins in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

New potent enkephalin analogs containing trifluoromethylamino acid residues

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Enkephalin analogs containing 4,4-difluoro-2-aminobutyric acid: synthesis and fluorine effect on the biological activity

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Modulation of the biological activity of thyrotropin-releasing hormone by alternate processing of pro-TRH.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Specificity of a Serum Peptidase Hydrolyzing Thyroliberin at the Pyroglutamyl-Histidine Bond

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Proteolytically stable peptides by incorporation of α-Tfm amino acids

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Regulation and cellular localization of the membrane-bound thyrotropin-releasing hormone-degrading enzyme in primary cultures of neuronal, glial and adenohypophyseal cells

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluoro-modified chemotactic peptides: fMLF analogues

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

N-formylmethionyl peptides as chemoattractants for leucocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Caged chemotactic peptides

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Further studies on the structural requirements for synthetic peptide chemoattractants

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Coiled-coils: stability, specificity, and drug delivery potential

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

MultiCoil: a program for predicting two- and three-stranded coiled coils

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Amino-acid sequence of rabbit skeletal tropomyosin and its coiled-coil structure

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Effects of side-chain characteristics on stability and oligomerization state of a de novo-designed model coiled-coil: 20 amino acid substitutions in position "d".

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Coiled coil domains: stability, specificity, and biological implications

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Electrostatic interactions control the parallel and antiparallel orientation of alpha-helical chains in two-stranded alpha-helical coiled-coils

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Leucine is the most stabilizing aliphatic amino acid in the d position of a dimeric leucine zipper coiled coil

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide.

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A chiroselective peptide replicator

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A synthetic peptide ligase

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Evaluation of the molecular interactions of fluorinated amino acids with native polypeptides

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

A coiled coil with a fluorous core

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Stabilization of coiled-coil peptide domains by introduction of trifluoroleucine

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Biosynthesis of a highly stable coiled-coil protein containing hexafluoroleucine in an engineered bacterial host

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Programmed self-sorting of coiled coils with leucine and hexafluoroleucine cores

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

De novo design of defined helical bundles in membrane environments

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Fluorous effect in proteins: de novo design and characterization of a four-alpha-helix bundle protein containing hexafluoroleucine

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

The role of interhelical ionic interactions in controlling protein folding and stability. De novo designed synthetic two-stranded alpha-helical coiled-coils

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Improving coiled-coil stability by optimizing ionic interactions

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021

Salt bridges destabilize a leucine zipper designed for maximized ion pairing between helices

1 reference

https://api.crossref.org/works/10.1002%2FEJOC.200500205

7 January 2021