Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer (Q57257741)

1 July 2019

title

Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer (English)

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1 July 2019

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Spiros Vlahopoulos

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author name string

Maria Adamaki

2

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1 July 2019

Nikolas Khoury

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1 July 2019

Vassilis Zoumpourlis

4

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1 July 2019

Istvan Boldogh

5

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1 July 2019

publication date

19 September 2018

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1 July 2019

Pharmacology & Therapeutics

published in

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1 July 2019

volume

194

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1 July 2019

page(s)

59-72

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1 July 2019

Formation of an 8-hydroxyguanine moiety in deoxyribonucleic acid on gamma-irradiation in aqueous solution.

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

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Ras proteins regulate multiple mitogenic pathways in A10 vascular smooth muscle cells

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Oncogenic Ha-Ras-induced Signaling Activates NF-κB Transcriptional Activity, Which Is Required for Cellular Transformation

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12 December 2020

Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

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Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation

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12 December 2020

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

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Comparison of the protective effect of melatonin with other antioxidants in the hamster kidney model of estradiol-induced DNA damage.

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Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions

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Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression

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Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells

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Missing pieces in the NF-kappaB puzzle

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Choreography of oxidative damage repair in mammalian genomes

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12 December 2020

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis

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12 December 2020

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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12 December 2020

DNA repair activity for oxidative damage and risk of lung cancer

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12 December 2020

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

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12 December 2020

Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation

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12 December 2020

Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.

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12 December 2020

Melatonin and cortisol serum levels in lung cancer patients at different stages of disease.

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12 December 2020

Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model

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12 December 2020

Base-excision repair of oxidative DNA damage by DNA glycosylases

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12 December 2020

Redox regulation of human OGG1 activity in response to cellular oxidative stress

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12 December 2020

Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions

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12 December 2020

UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles

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12 December 2020

The NF-kappaB regulatory network

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12 December 2020

TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.

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12 December 2020

Tumor exosomes inhibit differentiation of bone marrow dendritic cells

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12 December 2020

Nuclear translocation of p65 NF-kappaB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction

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12 December 2020

RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes

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12 December 2020

Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I⋅NF- kappa B-inducing kinase signaling pathway

1 reference

12 December 2020

Primary and metastatic lung tumors in the pediatric population: a review and 25-year experience at a large children's hospital

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12 December 2020

Redox regulation of the human dual specificity phosphatase YVH1 through disulfide bond formation

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12 December 2020

Interactive effect of cigarette smoking with human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) polymorphisms on the risk of lung cancer: a case-control study in Taiwan

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12 December 2020

Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression

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12 December 2020

Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts

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12 December 2020

Xenobiotic metabolism: a view through the metabolometer

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12 December 2020

Regulation of NF-kappaB responses by epigenetic suppression of IkappaBalpha expression in HCT116 intestinal epithelial cells.

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12 December 2020

CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF-κB, and MAPKs

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12 December 2020

Enrichment of Foxp3+ CD4 Regulatory T Cells in Migrated T Cells to IL-6– and IL-8–Expressing Tumors through Predominant Induction of CXCR1 by IL-6

1 reference

12 December 2020

TNF: a tumor-suppressing factor or a tumor-promoting factor?

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12 December 2020

8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes

1 reference

12 December 2020

Cordycepin Blocks Lung Injury-Associated Inflammation and Promotes BRCA1-Deficient Breast Cancer Cell Killing by Effectively Inhibiting PARP

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12 December 2020

Cross-Regulation Between Wnt and NF-κB Signaling Pathways

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12 December 2020

Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1

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12 December 2020

NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis

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12 December 2020

RelA Ser276 Phosphorylation-Coupled Lys310 Acetylation Controls Transcriptional Elongation of Inflammatory Cytokines in Respiratory Syncytial Virus Infection

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12 December 2020

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

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12 December 2020

Survival and death signals can predict tumor response to therapy after oncogene inactivation

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12 December 2020

Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection

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12 December 2020

Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).

1 reference

12 December 2020

8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice

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12 December 2020

Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium

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12 December 2020

NF-κB regulation: lessons from structures

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12 December 2020

Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1

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12 December 2020

Socioeconomic, Rural-Urban, and Racial Inequalities in US Cancer Mortality: Part I-All Cancers and Lung Cancer and Part II-Colorectal, Prostate, Breast, and Cervical Cancers

1 reference

12 December 2020

Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine

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12 December 2020

Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling

1 reference

12 December 2020

A CXCL1 paracrine network links cancer chemoresistance and metastasis

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12 December 2020

Elevated preoperative inflammatory markers based on neutrophil-to-lymphocyte ratio and C-reactive protein predict poor survival in resected non-small cell lung cancer

1 reference

12 December 2020

CD4+, IL17 and Foxp3 expression in different pTNM stages of operable non-small cell lung cancer and effects on disease prognosis

1 reference

12 December 2020

N-methylpurine DNA glycosylase and OGG1 DNA repair activities: opposite associations with lung cancer risk

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12 December 2020

Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

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12 December 2020

Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells.

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12 December 2020

CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

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12 December 2020

Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA

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12 December 2020

Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

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12 December 2020

Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis based on 22,475 subjects

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12 December 2020

Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analysis

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12 December 2020

Low integrated DNA repair score and lung cancer risk.

1 reference

12 December 2020

Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients

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12 December 2020

hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis

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12 December 2020

8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors

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12 December 2020

RAS transformation requires CUX1-dependent repair of oxidative DNA damage.

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12 December 2020

Novel signaling axis for ROS generation during K-Ras-induced cellular transformation

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12 December 2020

Cellular accumulation of Cys326-OGG1 protein complexes under conditions of oxidative stress

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12 December 2020

8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization.

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12 December 2020

Association of DNA base excision repair genes (OGG1, APE1 and XRCC1) polymorphisms with outcome to platinum-based chemotherapy in advanced nonsmall-cell lung cancer patients

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12 December 2020

Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells

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12 December 2020

Elevated pleural effusion IL-17 is a diagnostic marker and outcome predictor in lung cancer patients

1 reference

12 December 2020

IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity

1 reference

12 December 2020

ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment

1 reference

12 December 2020

Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

1 reference

12 December 2020

IL-12 regulates B7-H1 expression in ovarian cancer-associated macrophages by effects on NF-κB signalling

1 reference

12 December 2020

Lipocalin 2 is a regulator of macrophage polarization and NF-κB/STAT3 pathway activation

1 reference

12 December 2020

Feasibility of 8-OHdG formation and hOGG1 induction in PBMCs for assessing oxidative DNA damage in the lung of COPD patients

1 reference

12 December 2020

Enzyme kinetics of an alternative splicing isoform of mitochondrial 8-oxoguanine DNA glycosylase, ogg1-1b, and compared with the nuclear ogg1-1a

1 reference

12 December 2020

The role of 8-oxoguanine DNA glycosylase-1 in inflammation

1 reference

12 December 2020

NF-κB functions in tumor initiation by suppressing the surveillance of both innate and adaptive immune cells

1 reference

12 December 2020

Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway

1 reference

12 December 2020

Prognostic value of circulating inflammatory factors in non-small cell lung cancer: a systematic review and meta-analysis

1 reference

12 December 2020

miR141-CXCL1-CXCR2 signaling-induced Treg recruitment regulates metastases and survival of non-small cell lung cancer

1 reference

12 December 2020

Cellular and molecular immunology of lung cancer: therapeutic implications.

1 reference

12 December 2020

Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide

1 reference

12 December 2020

8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: role in asthma pathogenesis

1 reference

12 December 2020

Melatonin in patients with cancer receiving chemotherapy: a randomized, double-blind, placebo-controlled trial.

1 reference

12 December 2020

PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1

1 reference

12 December 2020

Inactivation of a common OGG1 variant by TNF-alpha in mammalian cells.

1 reference

12 December 2020

Expression of tumor necrosis factor-alpha-mediated genes predicts recurrence-free survival in lung cancer

1 reference

12 December 2020

The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer

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12 December 2020

Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

1 reference

12 December 2020

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts.

1 reference

12 December 2020

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

1 reference

12 December 2020

Recombinant mutated human TNF in combination with chemotherapy for stage IIIB/IV non-small cell lung cancer: a randomized, phase III study

1 reference

12 December 2020

EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB.

1 reference

12 December 2020

Disturbed Th17/Treg Balance in Patients with Non-small Cell Lung Cancer

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12 December 2020

JAK-STAT pathway activation in COPD.

1 reference

12 December 2020

Dynamic aberrant NF-κB spurs tumorigenesis: a new model encompassing the microenvironment

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12 December 2020

Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer.

1 reference

12 December 2020

Norepinephrine-induced myeloid-derived suppressor cells block T-cell responses via generation of reactive oxygen species

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12 December 2020

Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

1 reference

12 December 2020

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

1 reference

12 December 2020

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy

1 reference

12 December 2020

Type 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes

1 reference

12 December 2020

Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction

1 reference

12 December 2020

Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes

1 reference

12 December 2020

Association between Th17-related cytokines and risk of non-small cell lung cancer among patients with or without chronic obstructive pulmonary disease

1 reference

12 December 2020

The relationship between COPD and lung cancer

1 reference

12 December 2020

Prognostic significance of interleukin-17 in solid tumors: a meta-analysis.

1 reference

12 December 2020

URGCP promotes non-small cell lung cancer invasiveness by activating the NF-κB-MMP-9 pathway.

1 reference

12 December 2020

Targeted silencing of CXCL1 by siRNA inhibits tumor growth and apoptosis in hepatocellular carcinoma

1 reference

12 December 2020

Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation.

1 reference

12 December 2020

Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer

1 reference

12 December 2020

Regulation of PD-L1: a novel role of pro-survival signalling in cancer.

1 reference

12 December 2020

Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation

1 reference

12 December 2020

Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs

1 reference

12 December 2020

Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity.

1 reference

12 December 2020

Inflammatory cytokines and non-small cell lung cancer in a CT-scan screening cohort: Background review of the literature.

1 reference

12 December 2020

Transcription Factors and DNA Repair Enzymes Compete for Damaged Promoter Sites

1 reference

12 December 2020

The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis

1 reference

12 December 2020

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.

1 reference

12 December 2020

siRNA-induced TRAF6 knockdown promotes the apoptosis and inhibits the invasion of human lung cancer SPC-A1 cells

1 reference

12 December 2020

A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors

1 reference

12 December 2020

The Regulation of NF-κB Subunits by Phosphorylation

1 reference

12 December 2020

Melatonin as a potential anticarcinogen for non-small-cell lung cancer

1 reference

12 December 2020

DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study

1 reference

12 December 2020

IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer

1 reference

12 December 2020

Next-generation sequencing of Chinese stage IV lung cancer patients reveals an association between EGFR mutation status and survival outcome

1 reference

12 December 2020

Inflammation as a driver and vulnerability of KRAS mediated oncogenesis

1 reference

12 December 2020

Sequential measurements of serum matrix metalloproteinase 9 to monitor chemotherapy responses in patients with advanced non-small-cell lung cancer.

1 reference

12 December 2020

The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?

1 reference

12 December 2020

Pathogenesis of bronchopulmonary dysplasia: when inflammation meets organ development

1 reference

12 December 2020

Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.

1 reference

12 December 2020

Tumor-Derived CXCL1 Promotes Lung Cancer Growth via Recruitment of Tumor-Associated Neutrophils

1 reference

12 December 2020

KRAS and the Reality of Personalized Medicine in Non-small Cell Lung Cancer

1 reference

12 December 2020

Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment

1 reference

12 December 2020

Total and mutated EGFR quantification in cell-free DNA from non-small cell lung cancer patients detects tumor heterogeneity and presents prognostic value

1 reference

12 December 2020

The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer

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12 December 2020

Novel therapeutic targets on the horizon for lung cancer.

1 reference

12 December 2020

Reactive Oxygen Species Regulate T Cell Immune Response in the Tumor Microenvironment

1 reference

12 December 2020

Macrophage Inhibitory Cytokine-1 as a Novel Diagnostic and Prognostic Biomarker in Stage I and II Nonsmall Cell Lung Cancer

1 reference

12 December 2020

Lung cancer: current therapies and new targeted treatments

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12 December 2020

The CXCL8-CXCR1/2 pathways in cancer

1 reference

12 December 2020

Adipose-Derived Stem Cells Enhance Cancer Stem Cell Property and Tumor Formation Capacity in Lewis Lung Carcinoma Cells Through an Interleukin-6 Paracrine Circuit

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12 December 2020

Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

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12 December 2020

NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury.

1 reference

12 December 2020

Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents

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12 December 2020

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.

1 reference

12 December 2020

Efficacy of poly (ADP-ribose) polymerase inhibitor olaparib against head and neck cancer cells: Predictions of drug sensitivity based on PAR-p53-NF-κB interactions

1 reference

12 December 2020

Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression.

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12 December 2020

Clinical trials for BET inhibitors run ahead of the science

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12 December 2020

Low-frequency KRAS mutations are prevalent in lung adenocarcinomas

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12 December 2020

Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis

1 reference

12 December 2020

Unravelling signal escape through maintained EGFR activation in advanced non-small cell lung cancer (NSCLC): new treatment options

1 reference

12 December 2020

RAS-Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers

1 reference

12 December 2020

Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment

1 reference

12 December 2020

Elevated regulatory T cells, surface and intracellular CTLA-4 expression and interleukin-17 in the lung cancer microenvironment in humans.

1 reference

12 December 2020

Late-phase synthesis of IκBα insulates the TLR4-activated canonical NF-κB pathway from noncanonical NF-κB signaling in macrophages.

1 reference

12 December 2020

Unique aspects of the developing lung circulation: structural development and regulation of vasomotor tone

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12 December 2020

Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease

1 reference

12 December 2020

Inflammatory Cytokines and Lung Cancer Risk in 3 Prospective Studies

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12 December 2020

p38MAPK builds a hyaluronan cancer niche to drive lung tumorigenesis.

1 reference

12 December 2020

Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer

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12 December 2020

Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC.

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12 December 2020

Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3.

1 reference

12 December 2020

Mitochondrial DNA Damage Initiates Acute Lung Injury and Multi-Organ System Failure Evoked in Rats by Intra-Tracheal Pseudomonas Aeruginosa

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12 December 2020

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

1 reference

12 December 2020

Treatments for EGFR-mutant non-small cell lung cancer (NSCLC): The road to a success, paved with failures

1 reference

12 December 2020

Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters.

1 reference

12 December 2020

Base excision repair of oxidative DNA damage: from mechanism to disease.

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12 December 2020

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

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12 December 2020

Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells

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12 December 2020

OGG1-DNA interactions facilitate NF-κB binding to DNA targets

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12 December 2020

Smoking exposure, loss of forced expiratory volume in one second and the risk of lung cancer among patients with malignant disease who present with cardiac or pulmonary symptoms: a cross-sectional study

1 reference

12 December 2020

The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system

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12 December 2020

STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer

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12 December 2020

Human 8-oxoguanine DNA glycosylase gene polymorphism (Ser326Cys) and cancer risk: updated meta-analysis

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12 December 2020

Role of CXC group chemokines in lung cancer development and progression

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12 December 2020

Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

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12 December 2020

Nitric Oxide Synthase Activity Correlates with OGG1 in Ozone-Induced Lung Injury Animal Models

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12 December 2020

Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases

1 reference

12 December 2020

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

1 reference

12 December 2020

Neutrophil-Lymphocyte Ratio Is a Prognostic Marker in Patients with Locally Advanced (Stage IIIA and IIIB) Non-Small Cell Lung Cancer Treated with Combined Modality Therapy

1 reference

12 December 2020

Treatment advances in small cell lung cancer (SCLC).

1 reference

12 December 2020

Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients.

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12 December 2020

Harnessing the immune response to target tumors

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12 December 2020

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers

1 reference

12 December 2020

RAS Proteins and Their Regulators in Human Disease

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12 December 2020

Relationship of serum levels of interleukin 6, interleukin 8, and C-reactive protein with forced expiratory volume in first second in patients with mustard lung and chronic obstructive pulmonary diseases: systematic review and meta-analysis

1 reference

12 December 2020

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

1 reference

12 December 2020

Viral-induced Modulation of Multiple Checkpoint Proteins in Cancers

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12 December 2020

High systemic IL-6 is associated with worse prognosis in patients with non-small cell lung cancer.

1 reference

12 December 2020

Lung cancer as a paradigm for precision oncology in solid tumours

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12 December 2020

Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition

1 reference

12 December 2020

PD-L1 induced by IFN-γ from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer

1 reference

12 December 2020

Role and regulation of MKP-1 in airway inflammation.

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12 December 2020

TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts

1 reference

12 December 2020

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

1 reference

12 December 2020

Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode

1 reference

12 December 2020

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

1 reference

12 December 2020

Estimating the impact of a cancer diagnosis on life expectancy by socio-economic group for a range of cancer types in England

1 reference

12 December 2020

From biology to therapy: Improvements of therapeutic options in Lung cancer.

1 reference

12 December 2020

The prognostic value of interleukin-17 in lung cancer: A systematic review with meta-analysis based on Chinese patients

1 reference

12 December 2020

β-Catenin Directs Nuclear Factor-κB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle

1 reference

12 December 2020

Poly(ADP-Ribose)Polymerase-1 in Lung Inflammatory Disorders: A Review.

1 reference

12 December 2020

Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells.

1 reference

12 December 2020

Molecular genetics and cellular events of K-Ras-driven tumorigenesis.

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12 December 2020

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

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12 December 2020

8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions.

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12 December 2020

Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair

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12 December 2020

OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos.

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12 December 2020

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

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12 December 2020

10.1016/J.PHARMTHERA.2018.09.004

Identifiers

DOI

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1 July 2019

PMC publication ID

6504182

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1 July 2019

PubMed publication ID

30240635

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1 July 2019