A TFEB nuclear export signal integrates amino acid supply and glucose availability. (Q55691977)

http://europepmc.org/abstract/PMC/6041281

21 July 2018

title

A TFEB nuclear export signal integrates amino acid supply and glucose availability. (English)

1 reference

http://europepmc.org/abstract/PMC/6041281

21 July 2018

author

Roman Fischer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29992949%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Linxin Li

1

1 reference

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7 June 2020

Sarah Andrews

3

1 reference

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7 June 2020

Panagis Filippakopoulos

10

1 reference

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7 June 2020

author name string

Hans J Friedrichsen

2

1 reference

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7 June 2020

Sarah Picaud

4

1 reference

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7 June 2020

Laurent Volpon

5

1 reference

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7 June 2020

Kaochin Ngeow

6

1 reference

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7 June 2020

Georgina Berridge

7

1 reference

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7 June 2020

Katherine L B Borden

9

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7 June 2020

Colin R Goding

11

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7 June 2020

language of work or name

English

0 references

publication date

11 July 2018

1 reference

http://europepmc.org/abstract/PMC/6041281

21 July 2018

published in

Nature Communications

1 reference

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7 June 2020

volume

9

1 reference

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7 June 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29992949%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

2685

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Creative Commons Attribution 4.0 International

7 June 2020

copyright license

start time

11 July 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6041281/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6041281/fullTextXML

based on heuristic

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KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

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mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

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27 July 2018

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mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1

27 July 2018

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GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

27 July 2018

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27 July 2018

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Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

27 July 2018

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27 July 2018

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PPARGC1A/PGC-1α, TFEB and enhanced proteostasis in Huntington disease: defining regulatory linkages between energy production and protein-organelle quality control

27 July 2018

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Glycogen synthase kinase 3 inhibition promotes lysosomal biogenesis and autophagic degradation of the amyloid-β precursor protein

27 July 2018

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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

27 July 2018

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

27 July 2018

1 reference

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

27 July 2018

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TFEB links autophagy to lysosomal biogenesis

27 July 2018

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MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster.

27 July 2018

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REAP: A two minute cell fractionation method

27 July 2018

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27 July 2018

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27 July 2018

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Activation of the cellular DNA damage response in the absence of DNA lesions

27 July 2018

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

27 July 2018

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27 July 2018

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The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

27 July 2018

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CRM1 is an export receptor for leucine-rich nuclear export signals

27 July 2018

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Identification of a signal for rapid export of proteins from the nucleus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth

12 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

TFEB inhibits endothelial cell inflammation and reduces atherosclerosis

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Transcription Factor EB Controls Metabolic Flexibility during Exercise

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Protein kinase C controls lysosome biogenesis independently of mTORC1.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

TFEB and TFE3 are novel components of the integrated stress response

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

A tripartite transcription factor network regulates primordial germ cell specification in mice

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

TFEB: Pathogenic role and therapeutic target in Parkinson disease

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Regulation of TFEB and V-ATPases by mTORC1.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

MAP4K3 regulates body size and metabolism in Drosophila

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

A short amino acid sequence able to specify nuclear location

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041281

10.1038/S41467-018-04849-7

12 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29992949%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

ADS bibcode

2018NatCo...9.2685L

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29992949%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

29992949

1 reference