Influence of DNA repair gene polymorphisms on the yield of chromosomal aberrations. (Q54657687)

2 June 2018

title

Influence of DNA repair gene polymorphisms on the yield of chromosomal aberrations. (English)

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2 June 2018

4

Marcello Ceppi

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2 June 2018

author name string

Anne Kiuru

1

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2 June 2018

Carita Lindholm

2

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Iiris Heilimo

3

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Armi Koivistoinen

5

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Taina Ilus

6

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Ari Hirvonen

7

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Hannu Norppa

8

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Sisko Salomaa

9

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publication date

1 October 2005

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2 June 2018

Environmental and Molecular Mutagenesis

published in

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volume

46

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issue

3

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page(s)

198-205

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2 June 2018

Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations?

cites work

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Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays

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The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells

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Effects on sister chromatid exchange frequency of polymorphisms in DNA repair gene XRCC1 in smokers

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The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting

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FISH "painting" patterns resulting from complex exchanges

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XRCC1 keeps DNA from getting stranded

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DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers.

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The 399Gln polymorphism in the DNA repair gene XRCC1 modulates the genotoxic response induced in human lymphocytes by the tobacco-specific nitrosamine NNK

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Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco-specific nitrosamine NNK.

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Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks

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Use of biomarkers to characterize functions of polymorphic DNA repair genotypes

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XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

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Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair.

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Mechanisms of human DNA repair: an update

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Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

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Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

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Impact of Types of Lymphocyte Chromosomal Aberrations on Human Cancer Risk

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Single-strand interruptions in replicating chromosomes cause double-strand breaks

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Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population

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Long-term persistence of translocations in stable lymphocytes from victims of a radiological accident

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Domestic radon exposure and the frequency of stable or unstable chromosomal aberrations in lymphocytes

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Persistence of translocations after accidental exposure to ionizing radiation

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Distribution of radiation-induced exchange aberrations in human chromosomes 1, 2 and 4.

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Solution structure of the single-strand break repair protein XRCC1 N-terminal domain

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Role of maternal exposures and newborn genotypes on newborn chromosome aberration frequencies

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No adjustments are needed for multiple comparisons

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The transmission of FISH-painted patterns derived from complex chromosome exchanges

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The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis

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Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

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Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens

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XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis

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A proposed system for scoring structural aberrations detected by chromosome painting

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Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity

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Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: effects on levels of sister chromatid exchanges and chromosomal aberrations

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Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant

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Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA

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From genotype to phenotype: correlating XRCC1 polymorphisms with mutagen sensitivity

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Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo

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Identifiers

DOI

10.1002/EM.20155

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2 June 2018

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2 June 2018