Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types. (Q54310538)

27 May 2018

title

Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types. (English)

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27 May 2018

Nils J Fredriksson

1

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author name string

Lars Ny

series ordinal

2

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27 May 2018

Jonas A Nilsson

series ordinal

3

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27 May 2018

Erik Larsson

series ordinal

4

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27 May 2018

language of work or name

English

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publication date

10 November 2014

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27 May 2018

published in

Nature Genetics

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27 May 2018

volume

46

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27 May 2018

issue

12

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27 May 2018

page(s)

1258-1263

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27 May 2018

Evolution of the cancer genome

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Highly recurrent TERT promoter mutations in human melanoma

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Frequency of TERT promoter mutations in human cancers

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

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A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis

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Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

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Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

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Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine

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TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism

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12 December 2020

Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence

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Melanoma genome sequencing reveals frequent PREX2 mutations

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Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells

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12 December 2020

Identifiers

DOI

10.1038/NG.3141

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27 May 2018

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27 May 2018