Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy. (Q54253770)

http://europepmc.org/abstract/PMC/5852384

26 May 2018

title

Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy. (English)

1 reference

http://europepmc.org/abstract/PMC/5852384

26 May 2018

main subject

spinal muscular atrophy

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Ke Ning

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Mimoun Azzouz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Aziza Alrafiah

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Evangelia Karyka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Ian Coldicott

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Kayleigh Iremonger

4

1 reference

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7 June 2020

publication date

31 January 2018

1 reference

http://europepmc.org/abstract/PMC/5852384

26 May 2018

published in

Molecular Therapy. Methods & Clinical Development

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

81-89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5852384/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Survival Motor Neuron (SMN) protein is required for normal mouse liver development.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Spinal muscular atrophy: going beyond the motor neuron

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Survival motor neuron affects plastin 3 protein levels leading to motor defects

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Embryonic motor axon development in the severe SMA mouse

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Plastin 3 expression in discordant spinal muscular atrophy (SMA) siblings

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Association of plastin 3 expression with disease severity in spinal muscular atrophy only in postpubertal females.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5852384

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

13 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29552580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29552580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.OMTM.2018.01.007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29552580%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

29552580

1 reference