Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. (Q53544194)

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English	Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.	scientific article

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1 January 2020

Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin (English)

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1 January 2020

hepatocellular carcinoma

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RNA interference

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9

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Yangchao Chen

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Marie C Lin

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Hong Yao

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Hua Wang

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Ai-Qun Zhang

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Jun Yu

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Chee-kin Hui

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George K Lau

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Hsiang-fu Kung

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1 July 2007

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200-208

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1 January 2020

Strategies for retargeted gene delivery using vectors derived from lentiviruses.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

21 January 2018

Hepatocellular carcinoma

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https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

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Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S.cerevisiae telomeres

1 reference

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7 January 2021

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Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein

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7 January 2021

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Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs

1 reference

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7 January 2021

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Control of reproduction by Polycomb Group complexes in animals and plants.

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7 January 2021

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Role of polycomb group proteins in stem cell self-renewal and cancer.

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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1 reference

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7 January 2021

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Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

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Unlocking the potential of the human genome with RNA interference

1 reference

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7 January 2021

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RNA interference-based gene silencing in mice: the development of a novel therapeutical strategy

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Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus.

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Approaches for chemically synthesized siRNA and vector-mediated RNAi

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7 January 2021

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Microarrays of lentiviruses for gene function screens in immortalized and primary cells

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7 January 2021

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

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Induction of an interferon response by RNAi vectors in mammalian cells

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Knockdown by RNAi-proceed with caution

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7 January 2021

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Synthetic shRNAs as potent RNAi triggers

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

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Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

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WWOX gene restoration prevents lung cancer growth in vitro and in vivo

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Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.

1 reference

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p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

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The role of stathmin in the regulation of the cell cycle

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Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers.

1 reference

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7 January 2021

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Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma.

1 reference

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7 January 2021

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p53-mediated negative regulation of stathmin/Op18 expression is associated with G(2)/M cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

1 reference

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7 January 2021

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PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells

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