Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer. (Q53302549)

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13 February 2020

title

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer (English)

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13 February 2020

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4

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13 February 2020

author name string

Giridhar Mudduluru

1

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13 February 2020

Jonahunnatha N George-William

2

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13 February 2020

Santoshi Muppala

3

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13 February 2020

Regalla Kumarswamy

5

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13 February 2020

Laura D Nelson

6

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13 February 2020

Heike Allgayer

7

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publication date

1 June 2011

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13 February 2020

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13 February 2020

volume

31

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issue

3

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page(s)

185-197

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Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice

13 February 2020

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Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

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Multiple molecular targets in cancer chemoprevention by curcumin

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Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

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Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways

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Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.

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Cancer genes and the pathways they control

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Getting to the root of miRNA-mediated gene silencing

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Impaired microRNA processing enhances cellular transformation and tumorigenesis

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A developmental view of microRNA function

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An investigation of microRNAs mapping to breast cancer related genomic gain and loss regions

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OncomiRs: the discovery and progress of microRNAs in cancers

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miRNAs and their potential for use against cancer and other diseases

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miR-21 as a key regulator of oncogenic processes

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miR-21: a small multi-faceted RNA.

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MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

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miR-21-mediated tumor growth

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MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

21 January 2018

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Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium

21 January 2018

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

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miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism

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Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells

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BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1.

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An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation

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NRF-1, and AP-1 regulate the promoter of the human calpain small subunit 1 (CAPNS1) gene.

21 January 2018

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Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer

21 January 2018

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Induction of apoptosis by curcumin and its implications for cancer therapy

21 January 2018

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The molecular basis of oncogenes and tumor suppressor genes.

21 January 2018

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MicroRNA gene expression deregulation in human breast cancer

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The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

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Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome

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Chromatin structure analyses identify miRNA promoters

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Endogenous AP-1 levels necessary for oncogenic activity are higher than those sufficient to support normal growth

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Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation

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Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun

21 January 2018

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Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion

21 January 2018

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Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis

21 January 2018

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Curcumin selectively induces apoptosis in deregulated cyclin D1-expressed cells at G2 phase of cell cycle in a p53-dependent manner.

21 January 2018

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Src Induces Urokinase Receptor Gene Expression and Invasion/Intravasation via Activator Protein-1/p-c-Jun in Colorectal Cancer

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21 January 2018

Identifiers

DOI

10.1042/BSR20100065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815812%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference