The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. (Q53215353)

12 May 2018

title

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. (English)

1 reference

12 May 2018

0 references

0 references

1 reference

1 reference

3

Binder LI

1 reference

12 May 2018

author name string

Carmel G

series ordinal

1

1 reference

12 May 2018

Mager EM

series ordinal

2

1 reference

12 May 2018

Kuret J

series ordinal

4

1 reference

12 May 2018

language of work or name

English

0 references

publication date

1 December 1996

1 reference

12 May 2018

Journal of Biological Chemistry

published in

1 reference

12 May 2018

volume

271

1 reference

12 May 2018

issue

51

1 reference

12 May 2018

page(s)

32789-32795

1 reference

12 May 2018

A neuronal antigen in the brains of Alzheimer patients

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Evidence that transmitter-containing dystrophic neurites precede paired helical filament and Alz-50 formation within senile plaques in the amygdala of nondemented elderly and patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Binding of Alz 50 depends on Phe8 in tau synthetic peptides and varies between native and denatured tau proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Mapping of the Alz 50 epitope in microtubule-associated proteins tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

The distribution of Alz-50 immunoreactivity in the normal human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Reexpression of a developmentally regulated antigen in Down syndrome and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Alz-50 antibody recognizes Alzheimer-related neuronal changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

The distribution of tau in the mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Phosphorylation determines two distinct species of Tau in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Epitopes that span the tau molecule are shared with paired helical filaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Mitotic mechanisms in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A protein kinase associated with paired helical filaments in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Use of T7 RNA polymerase to direct expression of cloned genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

DNA Restriction Enzyme from E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A solid-phase screen for protein kinase substrate selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

13 The meaning of scatchard and hill plots

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

A population-based study of tau protein and ubiquitin in cerebrospinal fluid in 85-year-olds: relation to severity of dementia and cerebral atrophy, but not to the apolipoprotein E4 allele.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Subunit structure of paired helical filaments in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

The organization of the microtubule associated protein tau in Alzheimer paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Alzheimer paired helical filaments, untreated and pronase digested, studied by vertical platinum-carbon replication and high resolution transmission electron microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Biochemical assay of Alzheimer's disease--associated protein(s) in human brain tissue. A clinical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Monoclonal antibody Alz-50 reacts with bovine and human serum albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

FAC1, a novel gene identified with the monoclonal antibody Alz50, is developmentally regulated in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Tau protein and the neurofibrillary pathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Activation of phospholipase C-gamma by the concerted action of tau proteins and arachidonic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

Structure and novel exons of the human tau gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.51.32789

21 January 2018

Identifiers

DOI

10.1074/JBC.271.51.32789

1 reference

12 May 2018

1 reference

12 May 2018