HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations. (Q52645335)

http://europepmc.org/abstract/PMC/5896952

5 May 2018

title

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations. (English)

1 reference

http://europepmc.org/abstract/PMC/5896952

5 May 2018

author

Scott C Blanchard

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Jason Gorman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Russ Altman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Walther Mothes

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

11

Peter D Kwong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

9

James Arthos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Xiaochu Ma

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Maolin Lu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Daniel S Terry

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Xinyu Hong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Zhou Zhou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Hong Zhao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

James B Munro

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

21 March 2018

1 reference

http://europepmc.org/abstract/PMC/5896952

5 May 2018

published in

eLife

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

7 June 2020

cites work

1 reference

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Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop

22 May 2018

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22 May 2018

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22 May 2018

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HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

22 May 2018

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22 May 2018

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Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

22 May 2018

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Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

22 May 2018

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Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.

22 May 2018

1 reference

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Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

22 May 2018

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22 May 2018

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Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

22 May 2018

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Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

22 May 2018

1 reference

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

22 May 2018

1 reference

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

22 May 2018

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

22 May 2018

1 reference

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

22 May 2018

1 reference

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Ultra-stable organic fluorophores for single-molecule research

22 May 2018

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

22 May 2018

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Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer

22 May 2018

1 reference

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Molecular architecture of native HIV-1 gp120 trimers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments

22 May 2018

1 reference

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Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

22 May 2018

1 reference

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Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Subunit stoichiometry of human immunodeficiency virus type 1 envelope glycoprotein trimers during virus entry into host cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

HIV-1 membrane fusion: targets of opportunity

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: implications for therapeutic and vaccine strategies

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5896952

Site-specific protein labeling by Sfp phosphopantetheinyl transferase

13 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29561264

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29561264

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.34271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29561264%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

29561264

1 reference