Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents. (Q52569931)

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scientific article published on 10 April 2006

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English	Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.	scientific article published on 10 April 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents. (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

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author name string

Xinsheng Gu

1

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Sui Ke

2

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Duan Liu

3

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Tao Sheng

4

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Paul E Thomas

5

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Arnold B Rabson

6

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Michael A Gallo

7

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Wen Xie

8

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Yanan Tian

9

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

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publication date

10 April 2006

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Journal of Biological Chemistry

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PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

281

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PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

26

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3 May 2018

http://europepmc.org/abstract/MED/16608838

17882-17889

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

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Cytochrome P-450 3A4: regulation and role in drug metabolism

1 reference

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An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

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https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

1 reference

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21 January 2018

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

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CAR: detailing new models

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Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor

1 reference

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21 January 2018

Enterohepatic bile salt transporters in normal physiology and liver disease

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21 January 2018

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Regulation of cytochromes P450 during inflammation and infection.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Cytochrome P450 regulation and drug biotransformation during inflammation and infection

1 reference

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21 January 2018

Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Nuclear factor-kappaB: the enemy within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Interactions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity

1 reference

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21 January 2018

Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Induction of drug metabolism: the role of nuclear receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Drug-activated nuclear receptors CAR and PXR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Ah receptor and NF-kappaB interactions: mechanisms and physiological implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Toll-like receptor-4 regulation of hepatic Cyp3a11 metabolism in a mouse model of LPS-induced CNS inflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Role of mediator in transcriptional activation by the aryl hydrocarbon receptor

1 reference

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21 January 2018

The Universal Protein Resource (UniProt)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601302200

21 January 2018

Identifiers

10.1074/JBC.M601302200

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/16608838

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