The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells (Q51799484)

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scientific article published on 21 February 2007

Language	Label	Description	Also known as
English	The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells	scientific article published on 21 February 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

1 reference

based on heuristic

inferred from title

author name string

Alberto Kaumann

1

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

Annalese B T Semmler

2

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

Peter Molenaar

3

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

publication date

21 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

Naunyn-Schmiedeberg's Archives of Pharmacology

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Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

375

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

2

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

123-131

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

(-)-CGP 12177-induced increase of human atrial contraction through a putative third beta-adrenoceptor

1 reference

https://api.crossref.org/works/10.1007%2FS00210-007-0140-3

21 January 2018

A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

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Effects of a cardiotonic quinolinone derivative Y-20487 on the isoproterenol-induced positive inotropic action and cyclic AMP accumulation in rat ventricular myocardium: comparison with rolipram, Ro 20-1724, milrinone, and isobutylmethylxanthine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The affinity of (-)-propranolol for beta 1- and beta 2-adrenoceptors of human heart. Differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (-)-noradrenaline and (-)-adrenaline

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

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Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

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Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase inhibition and positive inotropy in failing human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of indolidan- and rolipram-sensitive cyclic nucleotide phosphodiesterases in canine and human cardiac microsomal fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)-Adrenaline elicits positive inotropic, lusitropic, and biochemical effects through β2-adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consistent with Gs coupling but not with Gi coupling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative beta 4-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[3H]-CGP 12177 binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta 1-adrenoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validity of (-)-[3H]-CGP 12177A as a radioligand for the 'putative beta4-adrenoceptor' in rat atrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Keynote review: phosphodiesterase-4 as a therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium. Quantitative discrepancies with binding and adenylate cyclase stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of cyclic AMP-dependent protein kinase in rat atria by (-)-CGP 12177 through an atypical beta-adrenoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bucindolol exerts agonistic activity on the propranolol-insensitive state of beta1-adrenoceptors in human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conservation of the cardiostimulant effects of (-)-norepinephrine across Ser49Gly and Gly389Arg beta(1)-adrenergic receptor polymorphisms in human right atrium in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta 3-adrenoceptor and rodent intestinal beta 3-adrenoceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective beta 1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through beta 2-adrenoceptors in human atrial myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cilostamide potentiates more the positive inotropic effects of (-)-adrenaline through beta(2)-adrenoceptors than the effects of (-)-noradrenaline through beta (1)-adrenoceptors in human atrial myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the effects of adrenaline and noradrenaline on human heart: the role of beta 1- and beta 2-adrenoceptors in the stimulation of adenylate cyclase and contractile force

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17318500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-007-0140-3

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/17318500

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