Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes (Q51570892)

7 April 2018

title

Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes (English)

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7 April 2018

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Joanne Teague

1

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7 April 2018

Amie Gyte

2

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Joanne E Peel

3

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Kimberley C Young

4

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Susan J G Loxham

5

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Rachel M Mayers

6

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Simon M Poucher

7

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publication date

14 April 2010

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7 April 2018

Journal of Pharmacological and Toxicological Methods

published in

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volume

63

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issue

1

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page(s)

15-23

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Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism

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Effect of dietary fat on the development of non-insulin dependent diabetes mellitus in obese Zucker diabetic fatty male and female rats

7 January 2021

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Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

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Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state.

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Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice

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Assessing the potential for alpha-glucosidase inhibitors in prediabetic states

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The Importance of -Cell Failure in the Development and Progression of Type 2 Diabetes

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Dynamic changes in {beta}-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in psammomys obesus: impact of glycemic control

7 January 2021

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Anatomical versus functional beta-cell mass in experimental diabetes

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Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice

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Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes

7 January 2021

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UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group

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Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

7 January 2021

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Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes.

7 January 2021

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Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult Rats

7 January 2021

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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

7 January 2021

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Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

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The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes?

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Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.

7 January 2021

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GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics

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Dynamics of insulin sensitivity, -cell function, and -cell mass during the development of diabetes in fa/fa rats

7 January 2021

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The dual peroxisome proliferator-activated receptor alpha/gamma activator muraglitazar prevents the natural progression of diabetes in db/db mice

7 January 2021

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7 January 2021

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Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone

7 January 2021

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Matrix metalloproteinases contribute to insulin insufficiency in Zucker diabetic fatty rats

7 January 2021

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10.1016/J.VASCN.2010.04.001

7 January 2021

Identifiers

DOI

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7 April 2018

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7 April 2018