Complement C3b/C4b receptor 1 (Knops blood group) (Q5156411)

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mammalian protein found in Homo sapiens

• complement receptor type 1
• C3-binding protein
• CD35 antigen
• complement receptor 1
• Knops blood group antigen
• CR1
• complement component (3b/4b) receptor 1 (Knops blood group)
• C3b/C4b receptor

edit

Language	Label	Description	Also known as
English	Complement C3b/C4b receptor 1 (Knops blood group)	mammalian protein found in Homo sapiens	complement receptor type 1 C3-binding protein CD35 antigen complement receptor 1 Knops blood group antigen CR1 complement component (3b/4b) receptor 1 (Knops blood group) C3b/C4b receptor

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P17927

part of

Sushi/SCR/CCP superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P17927

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P17927

encoded by

CR1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P17927

molecular function

virus receptor activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

complement component C3b receptor activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

complement component C4b receptor activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

complement component C3b binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

complement component C4b binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

cell component

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

plasma membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

integral component of plasma membrane

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Complement receptor is an inhibitor of the complement cascade

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

cell surface

determination method or standard

IDA

2 references

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

retrieved

8 April 2019

stated in

Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

extracellular exosome

determination method or standard

IDA

3 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17927&geneProductId=UniProtKB:P17927

determination method or standard

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17927&geneProductId=UniProtKB:P17927

determination method or standard

IDA

retrieved

26 September 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17927&geneProductId=UniProtKB:P17927

determination method or standard

IDA

secretory granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

ficolin-1-rich granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

extracellular exosome

determination method or standard

HDA

2 references

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

HDA

retrieved

8 April 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

HDA

biological process

negative regulation of complement activation, classical pathway

determination method or standard

IDA

2 references

retrieved

8 April 2019

stated in

Decay accelerating activity of complement receptor type 1 (CD35). Two active sites are required for dissociating C5 convertases

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

retrieved

8 April 2019

stated in

Complement receptor is an inhibitor of the complement cascade

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

immune system process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

positive regulation of serine-type endopeptidase activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

negative regulation of complement activation, alternative pathway

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Decay accelerating activity of complement receptor type 1 (CD35). Two active sites are required for dissociating C5 convertases

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

complement activation, classical pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

viral entry into host cell

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

viral process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

negative regulation of serine-type endopeptidase activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Complement receptor is an inhibitor of the complement cascade

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IDA

regulation of complement activation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

complement receptor mediated signaling pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

innate immune response

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P17927

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

IEA

neutrophil degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

regulation of regulatory T cell differentiation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17927

determination method or standard

TAS

Gene Atlas image

PBB GE CR1 206244 at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P17927

1 reference

stated in

Identifiers.org

has part(s)

sushi/SCR/CCP domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P17927

Identifiers

RefSeq protein ID

NP_000564

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1378

NP_000642

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1378

NP_001368780

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1378

UniProt protein ID

P17927

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P17927

Ensembl protein ID

ENSP00000356018

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356018

ENSP00000356020

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356020

ENSP00000383744

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000383744

ENSP00000356016

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356016

ENSP00000356019

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356019

ENSP00000434718

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000434718

ENSP00000436139

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000436139

Freebase ID

/m/04bk12

0 references

OpenAlex ID

C2910041089

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1GKG

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

1GKN

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

1PPQ

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

2Q7Z

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

2MCY

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

2MCZ

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

5FO9

1 reference

stated in

UniProt

UniProt protein ID

P17927

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(5 entries)

edit

• bswiki Knops sistem antigena
• cywiki CR1
• dewiki Komplementrezeptor 1
• enwiki Complement receptor 1
• ukwiki Рецептор комплементу 1

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

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