The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). (Q48925359)

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scientific article published in September 1996

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English	The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA).	scientific article published in September 1996

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

D. S. Fahmeed Hyder

4

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

author name string

D Manor

1

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

D L Rothman

2

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

G F Mason

3

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

O A Petroff

5

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

K L Behar

6

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

publication date

1 September 1996

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

Neurochemical Research

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

21

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

9

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

1031-1041

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

GABAergic mechanisms in the pathogenesis and treatment of epilepsy

1 reference

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Development of tolerance to the effects of vigabatrin (gamma-vinyl-GABA) on GABA release from rat cerebral cortex, spinal cord and retina

1 reference

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The flux from glucose to glutamate in the rat brain in vivo as determined by 1H-observed, 13C-edited NMR spectroscopy

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Studies on the control of 4-aminobutyrate metabolism in ‘synaptosomal’ and free rat brain mitochondria

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NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain

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Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.

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Neuronal-glial metabolism under depolarizing conditions. A 13C-n.m.r. study

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Effect of inhibitors of GABA transaminase on the synthesis, binding, uptake, and metabolism of GABA

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https://pubmed.ncbi.nlm.nih.gov/8897466

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Gabaculine and isogabaculine: biochemistry and pharmacology in mice

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1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo

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The level of GAD67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels.

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Regulatory properties of brain glutamate decarboxylase

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Differential localization of two glutamic acid decarboxylases (GAD65 and GAD67) in adult monkey visual cortex.

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gamma-Vinyl GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: effects on brain GABA metabolism in mice

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Different distributions of GAD65 and GAD67 mRNAs suggest that the two glutamate decarboxylases play distinctive functional roles.

1 reference

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Glutamine as precursor for the GABA and glutamate trasmitter pools

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Effects of gabaculine, a new potent inhibitor of gamma-amonobutyrate transaminase, on the brain gamma-amonobutyrate content and convulsions in mice

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First visualization of glutamate and GABA in neurones by immunocytochemistry

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Isolation and inhibitory activity of gabaculine, a new potent inhibitor of gamma-aminobutyrate aminotransferase produced by a Streptomyces

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Failure of GABAergic inhibition: a key to local and global seizures

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Regulation of gamma-aminobutyric acid synthesis in the brain

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Metabolic compartmentation of glutamate associated with the formation of gamma-aminobutyrate

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GABA as an inhibitory neurotransmitter in human cerebral cortex

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gamma-Vinyl GABA: effects of chronic administration on the metabolism of GABA and other amino compounds in rat brain

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Measurement of GABA following GABA-transaminase inhibition by gabaculine: a 1H and 31P NMR spectroscopic study of rat brain in vivo

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Cerebral metabolic compartmentation as revealed by nuclear magnetic resonance analysis of D-[1-13C]glucose metabolism

1 reference

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The in vivo inhibition of GABA-transaminase by gabaculine

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Regulation of transmitter gamma-aminobutyric acid (GABA) synthesis and metabolism illustrated by the effect of gamma-vinyl GABA and hypoglycemia

1 reference

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Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum

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1 reference

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1 reference

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12 December 2020

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The operation of the γ-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro

1 reference

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12 December 2020

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1 reference

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Alpha-ketoglutarate and malate uptake and metabolism by synaptosomes: further evidence for an astrocyte-to-neuron metabolic shuttle

1 reference

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1 reference

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12 December 2020

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1 reference

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1 reference

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12 December 2020

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NMR spectroscopy in neurochemistry

1 reference

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12 December 2020

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1 reference

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12 December 2020

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Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8897466

12 December 2020

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Identifiers

10.1007/BF02532413

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/8897466

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