APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice. (Q48282619)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Emma E Hamilton-Williams

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Raymond J Steptoe

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Peta Ls Reeves

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Rajeev Rudraraju

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Xiao Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

publication date

14 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

Immunology & Cell Biology

22 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

volume

95

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

page(s)

765-774

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

Autoantigen-specific memory CD4+ T cells are prevalent early in progression to Type 1 diabetes

22 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Allograft rejection mediated by memory T cells is resistant to regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Survival and function of MiHA epitope-specific host CD8 TM cells following ablative conditioning and HCT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Heterologous immunity provides a potent barrier to transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Steady-state antigen-expressing dendritic cells terminate CD4+ memory T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Tolerance in TCR/cognate antigen double-transgenic mice mediated by incomplete thymic deletion and peripheral receptor downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

NOD mice have a generalized defect in their response to transplantation tolerance induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+ T-cell effector differentiation by IL-2 modulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Induction of active tolerance and involvement of CD1d-restricted natural killer T cells in anti-CD3 F(ab')2 treatment-reversed new-onset diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Anergy in memory CD4+ T cells is induced by B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Mixed Chimerism, Lymphocyte Recovery, and Evidence for Early Donor-Specific Unresponsiveness in Patients Receiving Combined Kidney and Bone Marrow Transplantation to Induce Tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

CD4+ T Cell Help Impairs CD8+ T Cell Deletion Induced by Cross-presentation of Self-Antigens and Favors Autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Persistence of recipient lymphocytes in NOD mice after irradiation and bone marrow transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Drug-interaction studies evaluating T-cell proliferation reveal distinct activity of dasatinib and imatinib in combination with cyclosporine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

7 January 2021

Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

7 January 2021

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

7 January 2021

Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.48

7 January 2021

Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28611473

12 December 2020

inferred from PubMed ID database lookup

Kinetic analysis of oral tolerance: memory lymphocytes are refractory to oral tolerance.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28611473

12 December 2020

inferred from PubMed ID database lookup

Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28611473

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/ICB.2017.48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28611473%20AND%20SRC:MED&resulttype=core&format=json

release_ru6tyy63avatlhxsqbuke554qm

22 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ru6tyy63avatlhxsqbuke554qm

24 November 2022

mapped directly with Wikidata item

1 reference