The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury. (Q48173183)

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8 March 2020

title

The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury (English)

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8 March 2020

author

Jean-Christophe Marine

10

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8 March 2020

Giorgia Quadrato

3

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8 March 2020

Arnau Hervera

6

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8 March 2020

Radhika Puttagunta

11

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8 March 2020

author name string

Yashashree Joshi

1

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8 March 2020

Marília Grando Sória

2

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8 March 2020

Gizem Inak

4

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8 March 2020

Luming Zhou

5

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8 March 2020

Khizr I Rathore

7

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8 March 2020

Mohamed Elnaggar

8

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8 March 2020

Simone Di Giovanni

12

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8 March 2020

Magali Cucchiarini

9

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8 March 2020

language of work or name

English

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publication date

16 May 2015

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8 March 2020

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8 March 2020

volume

138

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8 March 2020

issue

Pt 7

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8 March 2020

page(s)

1843-1862

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Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains

8 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Regulation of p53--insights into a complex process

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Assembly of a new growth cone after axotomy: the precursor to axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Awakening guardian angels: drugging the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The histone acetyltransferase p300 promotes intrinsic axonal regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Molecular targets for axon regeneration: focus on the intrinsic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Production and characterization of adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Interleukin-6 promotes sprouting and functional recovery in lesioned organotypic hippocampal slice cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

STRING 8--a global view on proteins and their functional interactions in 630 organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Axon guidance of outgrowing corticospinal fibres in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

MdmX inhibits Smad transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Heterodimerization of glycosylated insulin-like growth factor-1 receptors and insulin receptors in cancer cells sensitive to anti-IGF1R antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The complexity of p53 stabilization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Mdmx as an essential regulator of p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

KLF family members regulate intrinsic axon regeneration ability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

RA-RAR-β counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

A novel function for p53: regulation of growth cone motility through interaction with Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Role of calpain-mediated p53 truncation in semaphorin 3A-induced axonal growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Identification and characterization of the first small molecule inhibitor of MDMX

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

MDMX inhibits the p300/CBP-mediated acetylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Membrane-associated STAT3 and PY-STAT3 in the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

SOCS3 deletion promotes optic nerve regeneration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

False resurrections: distinguishing regenerated from spared axons in the injured central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Regenerative growth of corticospinal tract axons via the ventral column after spinal cord injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The non-apoptotic role of p53 in neuronal biology: enlightening the dark side of the moon

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Axonal regeneration in adult CNS neurons--signaling molecules and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

MDM2 and MDM4: p53 regulators as targets in anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The role of serotonin in axon and dendrite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

The p53 orchestra: Mdm2 and Mdmx set the tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125

Glial inhibition of CNS axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWV125