Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons. (Q47812408)

PubMed publication ID

9671674

5 February 2018

http://europepmc.org/abstract/MED/9671674

title

Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons (English)

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12 May 2020

author name string

N Y Barnes

1

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12 May 2020

L Li

2

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12 May 2020

K Yoshikawa

3

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12 May 2020

L M Schwartz

4

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R W Oppenheim

5

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12 May 2020

C E Milligan

6

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12 May 2020

language of work or name

English

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publication date

1 August 1998

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PubMed publication ID

9671674

5 February 2018

http://europepmc.org/abstract/MED/9671674

published in

Journal of Neuroscience

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12 May 2020

volume

18

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issue

15

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12 May 2020

page(s)

5869-5880

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

12 May 2020

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Neuron death in vertebrate development: in vitro methods

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A gene expression screen

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Amyloid beta-protein precursor: new clues to the genesis of Alzheimer's disease

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Cell death in the development of the lateral motor column of the chick embryo

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Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

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Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

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Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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Presenilins Are Processed by Caspase-type Proteases

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β-Amyloid peptides as direct cholinergic neuromodulators: a missing link?

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Regression versus peripheral control of differentiation in motor hypoplasia

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12 December 2020

Cell death of motoneurons in the chick embryo spinal cord. I. A light and electron microscopic study of naturally occurring and induced cell loss during development

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

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12 December 2020

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

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A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells.

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12 December 2020

The β-Amyloid Precursor Protein of Alzheimer’s Disease Enhances Neuron Viability and Modulates Neuronal Polarity

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12 December 2020

Cold thoughts of death: the role of ICE proteases in neuronal cell death

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12 December 2020

Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons

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12 December 2020

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

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12 December 2020

Mechanisms of neuronal degeneration in Alzheimer's disease

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12 December 2020

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

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12 December 2020

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

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12 December 2020

Reduction of naturally occurring motoneuron death in vivo by a target-derived neurotrophic factor

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12 December 2020

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

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12 December 2020

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

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12 December 2020

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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12 December 2020

Amyloid beta peptide induces necrosis rather than apoptosis

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12 December 2020

Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

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12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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12 December 2020

Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates.

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12 December 2020

Thyroid hormone-induced gene expression changes in the developing frog limb

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12 December 2020

Fibrillar β-Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNSIn Vivo

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12 December 2020

Cell death of motoneurons in the chick embryo spinal cord. III. The differentiation of motoneurons prior to their induced degeneration following limb-bud removal

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12 December 2020

Gene activation is required for developmentally programmed cell death

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12 December 2020

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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12 December 2020

Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death

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12 December 2020

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

12 December 2020

DegenerationIn Vivoof Rat Hippocampal Neurons by Wild-Type Alzheimer Amyloid Precursor Protein Overexpressed by Adenovirus-Mediated Gene Transfer

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12 December 2020

Alzheimer's disease. A technical KO of amyloid-beta peptide.

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12 December 2020

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

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12 December 2020

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor

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12 December 2020

Cloning cell death genes.

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12 December 2020

Cell death induced by β-amyloid 1–40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis

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12 December 2020

Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.

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12 December 2020

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

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12 December 2020

Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains

1 reference

12 December 2020

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1 reference

12 December 2020

Beta APP gene expression is increased in the rat brain after motor neuron axotomy

1 reference

12 December 2020

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

12 December 2020

Amyloid β-protein Induces Necrotic Cell Death Mediated by ICE Cascade in PC12 Cells

1 reference

12 December 2020

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

12 December 2020

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

12 December 2020

Neuromuscular blockade increases motoneurone survival during normal cell death in the chick embryo

1 reference

12 December 2020

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

12 December 2020

Cell death during development of the nervous system

1 reference

12 December 2020

Apoptosis-mediated neurotoxicity induced by beta-amyloid and PrP fragments.

1 reference

12 December 2020

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

1 reference

12 December 2020

Peptide inhibitors of the ice protease family arrest programmed cell death of motoneurons in vivo and in vitro

1 reference

12 December 2020

Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons

1 reference

12 December 2020

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

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12 December 2020

Cell death of motoneurons in the chick embryo spinal cord. II. A quantitative and qualitative analysis of degeneration in the ventral root, including evidence for axon outgrowth and limb innervation prior to cell death

1 reference

12 December 2020

10.1523/JNEUROSCI.18-15-05869.1998

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793071&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793071&resulttype=core&format=json

12 May 2020

PubMed publication ID

9671674

1 reference