Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells (Q47764569)

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title

Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells (English)

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Kathy K Griendling

9

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author name string

Yoshihiro Taniyama

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Masuko Ushio-Fukai

2

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Hirofumi Hitomi

3

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Petra Rocic

4

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Michael J Kingsley

5

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Chun Pfahnl

6

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David S Weber

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R Wayne Alexander

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publication date

14 April 2004

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American Journal of Physiology - Cell Physiology

published in

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volume

287

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issue

2

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page(s)

C494-9

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

cites work

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Distinct cellular functions of MK2.

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators

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Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

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Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions

21 January 2018

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Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

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p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy

21 January 2018

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Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells

21 January 2018

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The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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Angiotensin II Activates pp60 c- src in Vascular Smooth Muscle Cells

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Identifiers

DOI

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5 February 2018

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5 February 2018