Mitogenic factors accelerate later-age diseases: insulin as a paradigm (Q47756026)

5 February 2018

review article

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title

Mitogenic factors accelerate later-age diseases: insulin as a paradigm (English)

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5 February 2018

author name string

Lev-Ran A

series ordinal

1

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5 February 2018

publication date

1 May 1998

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5 February 2018

Mechanisms of Ageing and Development

published in

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5 February 2018

volume

102

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5 February 2018

issue

1

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5 February 2018

page(s)

95-113

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5 February 2018

Tissue-type plasminogen activator antigen and plasminogen activator inhibitor in diabetes mellitus

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Role of the time factor in signaling specificity: application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases

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Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

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Calories, cell proliferation, and proviral expression in autoimmunity and cancer

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Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome

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Sex differences in insulin levels in older adults and the effect of body size, estrogen replacement therapy, and glucose tolerance status. The Rancho Bernardo Study, 1984-1987.

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Hyperinsulinaemia as a predictor of coronary heart disease mortality in a healthy population: the Paris Prospective Study, 15-year follow-up

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Exogenous insulin administration and cardiovascular risk in non-insulin-dependent and insulin-dependent diabetes mellitus

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Chronologic and Physiologic Age Affect Replicative Life-Span of Fibroblasts from Diabetic, Prediabetic, and Normal Donors

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Overexpression of plasminogen activator inhibitor type-1 in senescent fibroblasts from normal subjects and those with Werner syndrome

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7 January 2021

Insulin Resistance Implications for Type II Diabetes Mellitus and Coronary Heart Disease

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Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?

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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

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Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

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Glucose tolerance, plasma insulin, HDL cholesterol and obesity: 12-year follow-up and development of coronary heart disease in Edinburgh men

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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In situ analysis of changes in telomere size during replicative aging and cell transformation

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7 January 2021

Does gene expression play any role in the mechanism of the antiaging effect of dietary restriction?

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Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators.

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Multiple metabolic abnormalities in normal glucose tolerant relatives of NIDDM families

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Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

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Insulin treatment, endogenous insulin concentration, and ECG abnormalities in diabetic Pima Indians. Cross-sectional and prospective analyses

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Calorie restriction and cellular proliferation in various tissues of the female Swiss Webster mouse

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McCay's hypothesis: undernutrition and longevity

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Retardation of the Aging Processes in Rats by Food Restriction

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Dietary restriction alters characteristics of glucose fuel use.

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Accelerated telomere shortening in ataxia telangiectasia

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Hyperinsulinemia. A link between hypertension obesity and glucose intolerance

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Cardiovascular disease risk factors as predictors of type 2 (non-insulin-dependent) diabetes mellitus in elderly subjects

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Low incidence of fatal coronary heart disease in Pima Indians despite high prevalence of non-insulin-dependent diabetes

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Decrease by chronic energy intake restriction of cellular proliferation in the intestinal epithelium and lymphoid organs in autoimmunity-prone mice

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Banting lecture 1988. Role of insulin resistance in human disease

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Pathophysiology of insulin resistance in human disease.

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Insulin resistance, its consequences, and coronary heart disease. Must we choose one culprit?

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Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction

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Abnormalities in proliferation and protein synthesis in skin fibroblast cultures from patients with diabetes mellitus

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Demonstration of insulin resistance in coronary artery disease documented with angiography.

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Effect of human growth hormone and insulin on [3H]thymidine incorporation, cell cycle progression, and cyclin D expression in 3T3-F442A preadipose cells

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Coronary Heart Disease Incidence and Cardiovascular Mortality in Busselton with Reference to Glucose and Insulin Concentrations

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The role of insulin in age-related sex differences of cardiovascular risk profile and morbidity

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Is insulin really a heart disease risk factor

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Caloric Restriction: Conservation of in Vivo Cellular Replicative Capacity Accompanies Life-Span Extension in Mice

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Dissociation between urinary albumin excretion and variables associated with insulin resistance in a healthy population

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Identifiers

DOI

1 reference

5 February 2018

1 reference

5 February 2018