Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues. (Q47604922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610082%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues (English)

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10 March 2020

2

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10 March 2020

Torsten Goldmann

9

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10 March 2020

author name string

D S Lang

1

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10 March 2020

U Heilenkötter

3

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10 March 2020

W Schumm

4

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10 March 2020

O Behrens

5

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10 March 2020

R Simon

6

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10 March 2020

M Reck

7

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10 March 2020

E Vollmer

8

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10 March 2020

publication date

9 March 2014

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Pathology and Oncology Research

10 March 2020

published in

1 reference

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10 March 2020

volume

20

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10 March 2020

issue

3

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10 March 2020

page(s)

727-732

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Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis

10 March 2020

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UPA and PAI-1 analysis from fixed tissues - new perspectives for a known set of predictive markers.

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Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell–like Properties in Breast Cancer Cells

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Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression

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The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae.

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Estrogen inhibits transforming growth factor beta signaling by promoting Smad2/3 degradation

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Estrogen and antiestrogens alter breast cancer invasiveness by modulating the transforming growth factor‐β signaling pathway

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TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

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ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion.

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Smad4-independent TGF-beta signaling in tumor cell migration

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TGF-beta signaling: positive and negative effects on tumorigenesis

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uPA and PAI-1-Related Signaling Pathways Differ between Primary Breast Cancers and Lymph Node Metastases

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PAI-1: An Integrator of Cell Signaling and Migration

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BAMBI gene is epigenetically silenced in subset of high-grade bladder cancer

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Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

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TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.

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Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.

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Signalling networks associated with urokinase‐type plasminogen activator (uPA) and its inhibitor PAI‐1 in breast cancer tissues: new insights from protein microarray analysis

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Prospective Biomarker Trials Chemo N0 and NNBC-3 Europe Validate the Clinical Utility of Invasion Markers uPA and PAI-1 in Node-Negative Breast Cancer.

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24610082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Optimized immunohistochemistry in combination with image analysis: a reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24610082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The HOPE technique opens up a multitude of new possibilities in pathology.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24610082