Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. (Q47597394)

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28 December 2019

title

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. (English)

1 reference

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28 December 2019

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acute myeloid leukemia

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author

Daniel G Tenen

9

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28 December 2019

Frank Rosenbauer

1

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28 December 2019

Steven N. Fiering

8

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28 December 2019

5

Michelle M Le Beau

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28 December 2019

author name string

Katharina Wagner

2

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28 December 2019

Jeffery L Kutok

3

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28 December 2019

Hiromi Iwasaki

4

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28 December 2019

Yutaka Okuno

6

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28 December 2019

Koichi Akashi

7

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28 December 2019

language of work or name

English

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publication date

16 May 2004

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28 December 2019

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28 December 2019

volume

36

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28 December 2019

issue

6

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28 December 2019

page(s)

624-630

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Diversification of haematopoietic stem cells to specific lineages.

28 December 2019

cites work

1 reference

Disruption of differentiation in human cancer: AML shows the way.

21 January 2018

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Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

21 January 2018

1 reference

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

21 January 2018

1 reference

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

21 January 2018

1 reference

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha

21 January 2018

1 reference

PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors

21 January 2018

1 reference

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

21 January 2018

1 reference

Regulation of B lymphocyte and macrophage development by graded expression of PU.1.

21 January 2018

1 reference

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor

21 January 2018

1 reference

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

21 January 2018

1 reference

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

1 reference

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

21 January 2018

1 reference

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

21 January 2018

1 reference

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

21 January 2018

1 reference

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

21 January 2018

1 reference

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

21 January 2018

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myc function and regulation

21 January 2018

1 reference

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

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Reversible tumorigenesis by MYC in hematopoietic lineages

21 January 2018

1 reference

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

21 January 2018

1 reference

Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia

21 January 2018

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Regulation of the PU.1 gene by distal elements

21 January 2018

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