Epigenetics and cerebral organoids: promising directions in autism spectrum disorders (Q47562578)

24 February 2018

6 references

13 March 2019

8 September 2019

12 September 2019

11 October 2019

25 September 2020

29 April 2021

Epigenetics and cerebral organoids: promising directions in autism spectrum disorders (English)

1 reference

24 February 2018

main subject

autism spectrum disorder

1 reference

regulation of gene expression

13 March 2019

1 reference

8 September 2019

1 reference

12 September 2019

1 reference

11 October 2019

1 reference

25 September 2020

1 reference

29 April 2021

1 reference

Mirolyuba Ilieva

2

0 references

author name string

Sheena Louise Forsberg

series ordinal

1

1 reference

24 February 2018

Tanja Maria Michel

series ordinal

3

1 reference

24 February 2018

language of work or name

1 reference

10 January 2018

7 references

24 February 2018

13 March 2019

8 September 2019

12 September 2019

11 October 2019

25 September 2020

29 April 2021

Translational Psychiatry

7 references

24 February 2018

13 March 2019

8 September 2019

12 September 2019

11 October 2019

25 September 2020

29 April 2021

8

1 reference

24 February 2018

issue

1

1 reference

24 February 2018

page(s)

14

1 reference

24 February 2018

Creative Commons Attribution

copyright license

6 references

13 March 2019

8 September 2019

12 September 2019

11 October 2019

25 September 2020

29 April 2021

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

22 May 2018

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Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming

22 May 2018

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Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

22 May 2018

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Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

22 May 2018

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Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells

22 May 2018

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Using iPS Cells toward the Understanding of Parkinson's Disease

22 May 2018

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FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

22 May 2018

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Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

22 May 2018

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Autism beyond diagnostic categories: characterization of autistic phenotypes in schizophrenia

22 May 2018

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22 May 2018

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The use of stem cells to study autism spectrum disorder

22 May 2018

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Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum

22 May 2018

1 reference

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Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases

22 May 2018

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DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways

22 May 2018

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Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder

22 May 2018

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Hypermethylation of the enolase gene (ENO2) in autism

22 May 2018

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Drug discovery through stem cell-based organoid models

22 May 2018

1 reference

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Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

22 May 2018

1 reference

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SOX2 and OCT4 mRNA-expressing cells, detected by molecular beacons, localize to the center of neurospheres during differentiation

22 May 2018

1 reference

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Common DNA methylation alterations in multiple brain regions in autism.

22 May 2018

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Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

22 May 2018

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The expanding genomic landscape of autism: discovering the 'forest' beyond the 'trees'

22 May 2018

1 reference

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Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

22 May 2018

1 reference

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Cell culture: a better brew

22 May 2018

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Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum

22 May 2018

1 reference

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Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits

22 May 2018

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Induced pluripotent stem cells from human hair follicle mesenchymal stem cells

22 May 2018

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Autism risk factors: genes, environment, and gene-environment interactions

22 May 2018

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Generation of human induced pluripotent stem cells from urine samples.

22 May 2018

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DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli

22 May 2018

1 reference

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Brain transcriptional and epigenetic associations with autism

22 May 2018

1 reference

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GABA system dysfunction in autism and related disorders: from synapse to symptoms

22 May 2018

1 reference

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The role of oxidative stress in depressive disorders

22 May 2018

1 reference

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A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities

22 May 2018

1 reference

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Small molecules enable highly efficient neuronal conversion of human fibroblasts

22 May 2018

1 reference

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Direct conversion of fibroblasts into stably expandable neural stem cells

22 May 2018

1 reference

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Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation.

22 May 2018

1 reference

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

22 May 2018

1 reference

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Prader-Willi syndrome and autism spectrum disorders: an evolving story

22 May 2018

1 reference

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Neuron-specific impairment of inter-chromosomal pairing and transcription in a novel model of human 15q-duplication syndrome

22 May 2018

1 reference

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Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism.

22 May 2018

1 reference

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Role of MeCP2, DNA methylation, and HDACs in regulating synapse function

22 May 2018

1 reference

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Induced pluripotent stem cells: a new tool to confront the challenge of neuropsychiatric disorders

22 May 2018

1 reference

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Somatic coding mutations in human induced pluripotent stem cells

22 May 2018

1 reference

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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

22 May 2018

1 reference

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Annual Research Review: The promise of stem cell research for neuropsychiatric disorders

22 May 2018

1 reference

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3D cell culture: a review of current approaches and techniques

22 May 2018

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The role of neurotrophic factors in autism.

22 May 2018

1 reference

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Epigenetics, Copy Number Variation, and Other Molecular Mechanisms Underlying Neurodevelopmental Disabilities: New Insights and Diagnostic Approaches

22 May 2018

1 reference

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Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders

22 May 2018

1 reference

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Genetic and brain structure anomalies in autism spectrum disorders. Towards an understanding of the aetiopathogenesis?

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

22 May 2018

1 reference

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Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function

22 May 2018

1 reference

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Ube3a is required for experience-dependent maturation of the neocortex.

22 May 2018

1 reference

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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

22 May 2018

1 reference

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MECP2 promoter methylation and X chromosome inactivation in autism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals

22 May 2018

1 reference

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

22 May 2018

1 reference

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Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number.

22 May 2018

1 reference

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Genomic imprinting in the development and evolution of psychotic spectrum conditions

22 May 2018

1 reference

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Altered glial cell line-derived neurotrophic factor (GDNF) concentrations in the brain of patients with depressive disorder: a comparative post-mortem study

22 May 2018

1 reference

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Advances in autism genetics: on the threshold of a new neurobiology

22 May 2018

1 reference

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Analysis of X chromosome inactivation in autism spectrum disorders

22 May 2018

1 reference

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

22 May 2018

1 reference

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Autism: the quest for the genes

22 May 2018

1 reference

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The third dimension bridges the gap between cell culture and live tissue

22 May 2018

1 reference

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Simplifying the extracellular matrix for 3-D cell culture and tissue engineering: a pragmatic approach

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Epigenetic mechanisms in the context of complex diseases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

MeCP2 in Rett syndrome: transcriptional repressor or chromatin architectural protein?

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Epigenetic gene regulation: linking early developmental environment to adult disease

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Capturing complex 3D tissue physiology in vitro

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Characteristics of fetal anticonvulsant syndrome associated autistic disorder.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Reelin glycoprotein: structure, biology and roles in health and disease

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

22 May 2018

The genetics of autism

1 reference

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Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation.

22 May 2018

1 reference

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Rett syndrome and MeCP2: linking epigenetics and neuronal function

22 May 2018

1 reference

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Altered levels of Reelin and its isoforms in schizophrenia and mood disorders

22 May 2018

1 reference

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Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Ring X and other structural X chromosome abnormalities: X inactivation and phenotype

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Looping versus linking: toward a model for long-distance gene activation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Autism or atypical autism in maternally but not paternally derived proximal 15q duplication

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Expression of the homeobox-containing genes EN1 and EN2 in human fetal midgestational medulla and cerebellum

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Autism in Angelman syndrome: a population-based study

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Nonhuman primate model of alcohol abuse: effects of early experience, personality, and stress on alcohol consumption

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Assembly of functionally integrated human forebrain spheroids

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Self-organized developmental patterning and differentiation in cerebral organoids

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Histone Acetylome-wide Association Study of Autism Spectrum Disorder.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

3D human tissue culture: modeling environmental effects on the stem cell epigenome

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Neurobiology meets genomic science: the promise of human-induced pluripotent stem cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Analysis of MECP2 Gene Copy Number in Boys With Autism

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Epigenetic regulation of the neural transcriptome: the meaning of the marks.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Evaluation of diagnostic and therapeutic services in German university hospitals for adults with autism spectrum disorder (ASD)

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Increased xanthine oxidase in the thalamus and putamen in depression

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Evaluation of autism traits in Angelman syndrome: a resource to unfold autism genes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Evidence for oxidative stress in the frontal cortex in patients with recurrent depressive disorder--a postmortem study

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Brief report: non-random X chromosome inactivation in females with autism.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Psychotic disorders in Prader-Willi syndrome.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5802583

Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41398-017-0062-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41398-017-0062-X

7 January 2021

inferred from DOI database lookup

Alteration of the pro-oxidant xanthine oxidase (XO) in the thalamus and occipital cortex of patients with schizophrenia

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41398-017-0062-X

7 January 2021

inferred from DOI database lookup

Ciliary neurotrophic factor (CNTF) genotypes: influence on choline acetyltransferase (ChAT) and acetylcholine esterase (AChE) activities and neurotrophin 3 (NT3) concentration in human post mortem brain tissue

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29317608

12 December 2020

inferred from PubMed ID database lookup

Cu, Zn- and Mn-superoxide dismutase levels in brains of patients with schizophrenic psychosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29317608

12 December 2020

inferred from PubMed ID database lookup

Three-Dimensional Cell Cultures in Drug Discovery and Development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29317608

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41398-017-0062-X

1 reference

24 February 2018

PMC publication ID

5802583

1 reference

24 February 2018

PubMed publication ID

29317608

1 reference

24 February 2018