Overexpression of 5-Lipoxygenase Worsens the Phenotype of a Mouse Model of Tauopathy (Q47412565)

15 January 2018

http://europepmc.org/abstract/MED/29128902

1 reference

29 December 2023

https://doi.org/10.1007/s12035-023-03283-1

title

Overexpression of 5-Lipoxygenase Worsens the Phenotype of a Mouse Model of Tauopathy (English)

1 reference

15 January 2018

http://europepmc.org/abstract/MED/29128902

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Phillip F Giannopoulos

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

11 November 2017

1 reference

15 January 2018

http://europepmc.org/abstract/MED/29128902

published in

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

5926-5936

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

Tau pathology and neurodegeneration

8 June 2020

cites work

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

21 January 2018

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Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration

21 January 2018

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Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy

21 January 2018

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The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.

21 January 2018

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The 5-Lipoxygenase as modulator of Alzheimer's γ-secretase and therapeutic target

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Putative role of neuronal 5-lipoxygenase in an aging brain.

21 January 2018

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Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

21 January 2018

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Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase

21 January 2018

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Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease

21 January 2018

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Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy

21 January 2018

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5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease

21 January 2018

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Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

21 January 2018

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Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice

21 January 2018

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12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice

21 January 2018

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Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model

21 January 2018

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Novel lipid signaling pathways in Alzheimer's disease pathogenesis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain

21 January 2018

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5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29128902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tau in physiology and pathology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29128902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12035-017-0817-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29128902%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference