The twilight of immunity: emerging concepts in aging of the immune system (Q47291933)

13 January 2018

review article

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title

The twilight of immunity: emerging concepts in aging of the immune system (English)

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13 January 2018

author

Janko Nikolich-Žugich

series ordinal

1

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13 January 2018

language of work or name

English

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publication date

14 December 2017

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13 January 2018

published in

Nature Immunology

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13 January 2018

volume

19

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13 January 2018

issue

1

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13 January 2018

page(s)

10-19

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13 January 2018

Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo

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Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans

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A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

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The aged lymphoid tissue environment fails to support naïve T cell homeostasis

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The generation of memory B cells is maintained, but the antibody response is not, in the elderly after repeated influenza immunizations

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Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection

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Aging increases cell-to-cell transcriptional variability upon immune stimulation

21 January 2018

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The chromatin accessibility signature of human immune aging stems from CD8+ T cells.

21 January 2018

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21 January 2018

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21 January 2018

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Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

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Structural and functional changes to lymph nodes in ageing mice

21 January 2018

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Variation in the human immune system is largely driven by non-heritable influences

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How does cytomegalovirus factor into diseases of aging and vaccine responses, and by what mechanisms?

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice

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The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

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10.1038/S41590-017-0006-X

Identifiers

DOI

1 reference

13 January 2018

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13 January 2018