Ribosome dysfunction is an early event in Alzheimer's disease. (Q46738279)

PubMed publication ID

16207876

24 December 2017

http://europepmc.org/abstract/MED/16207876

title

Ribosome dysfunction is an early event in Alzheimer's disease (English)

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12 May 2020

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5

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12 May 2020

William R. Markesbery

2

object named as

William R Markesbery

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12 May 2020

author name string

Qunxing Ding

1

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12 May 2020

Qinghua Chen

3

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12 May 2020

Feng Li

4

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12 May 2020

language of work or name

English

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publication date

1 October 2005

1 reference

PubMed publication ID

16207876

24 December 2017

http://europepmc.org/abstract/MED/16207876

published in

Journal of Neuroscience

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12 May 2020

volume

25

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12 May 2020

issue

40

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12 May 2020

page(s)

9171-9175

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describes a project that uses

12 May 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725754/fullTextXML

inferred from PubMed Central ID database lookup

cites work

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

1 reference

12 December 2020

Mild cognitive impairment: clinical characterization and outcome

1 reference

12 December 2020

Mild cognitive impairment represents early-stage Alzheimer disease

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Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study

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Differential expression of phosphorylated translation initiation factor 2 alpha in Alzheimer's disease and Creutzfeldt-Jakob's disease

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Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease

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12 December 2020

Molecular network and functional implications of macromolecular tRNA synthetase complex

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Pre-ribosomes on the road from the nucleolus to the cytoplasm

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Pathology and pathways of Alzheimer's disease with an update on new developments in treatment.

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Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

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Mild cognitive impairment: directions for future research

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Ribosome assembly in eukaryotes

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12 December 2020

Activation of the cell stress kinase PKR in Alzheimer's disease and human amyloid precursor protein transgenic mice

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12 December 2020

Selective translational control and nonspecific posttranscriptional regulation of ribosomal protein gene expression during development and regeneration of rat liver

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Ubiquitin depletion as a key mediator of toxicity by translational inhibitors

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An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease

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A hamster temperature-sensitive alanyl-tRNA synthetase mutant causes degradation of cell-cycle related proteins and apoptosis.

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12 December 2020

Ribosome biogenesis: of knobs and RNA processing

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12 December 2020

Phosphorylated eukaryotic translation factor 4E is elevated in Alzheimer brain.

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12 December 2020

Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures.

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12 December 2020

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

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12 December 2020

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

1 reference

12 December 2020

Neuropathological stageing of Alzheimer-related changes

1 reference

12 December 2020

Mild cognitive impairment in the elderly: predictors of dementia

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Alzheimer's disease-associated reduction of polysomal mRNA translation

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12 December 2020

Preparation of a cell-free extract from rat brain which can initiate protein synthesis in vitro

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Alzheimer's disease brain: alterations in RNA levels and in a ribonuclease-inhibitor complex

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Mammalian aminoacyl-tRNA synthetases.

1 reference

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Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study

1 reference

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Aging, Memory, and Mild Cognitive Impairment

1 reference

12 December 2020

10.1523/JNEUROSCI.3040-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725754&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725754&resulttype=core&format=json

12 May 2020

PubMed publication ID

16207876

1 reference