Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus. (Q46529938)

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scientific article published in May 2006

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English	Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.	scientific article published in May 2006

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21 January 2020

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus (English)

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21 January 2020

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Qin Xu

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21 January 2020

Aubrey Bernardo

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21 January 2020

David Walker

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21 January 2020

Tiffany Kanegawa

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21 January 2020

Robert W Mahley

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21 January 2020

Yadong Huang

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1 May 2006

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21 January 2020

Journal of Neuroscience

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21 January 2020

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21 January 2020

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21 January 2020

4985-4994

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21 January 2020

Specific regional transcription of apolipoprotein E in human brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E expression by neurons surviving excitotoxic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E and cognitive performance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of apolipoproteins from murine microglia. Identification of a low density lipoprotein-like apolipoprotein J-rich but E-poor spherical particle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and regulation of apolipoprotein E during the differentiation of human neuronal precursor NT2/D1 cells into postmitotic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the apolipoprotein E gene in the skin is controlled by a unique downstream enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and processing of apolipoprotein E in human brain cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E is upregulated in olfactory bulb glia following peripheral receptor lesion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New frontiers in Alzheimer's disease genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE deficiency compromises the blood brain barrier especially after injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgens protect against apolipoprotein E4-induced cognitive deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of neuronal apolipoprotein E in human brain with cerebral infarction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choroid plexus ageing of the brain and Alzheimer s disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal apolipoprotein E is not synthesized in neuron after focal ischemia in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cells can form germ cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-serine-mediated release of apolipoprotein E and lipids from microglial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular apolipoprotein e expression and recruitment from circulation to modulate smooth muscle cell response to endothelial denudation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LRP-mediated clearance of Abeta is inhibited by KPI-containing isoforms of APP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The choroid plexus removes beta-amyloid from brain cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E and Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular pathology of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the human apolipoprotein E gene in cultured mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kainic acid induced seizures: neurochemical and histopathological changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE immunoreactivity and microglial cells in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E ϵ4 and cerebral hemorrhage associated with amyloid angiopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein(A): physiologic function, association with atherosclerosis, and effects of lipid-lowering drug therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of a liver-specific enhancer in the apolipoprotein E/C-I/C-II gene locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E alleles as risk factors in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurons of the human frontal cortex display apolipoprotein E immunoreactivity: implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor AP-2 regulates human apolipoprotein E gene expression in astrocytoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform‐Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood‐Brain Barrier Transport of Circulating Alzheimer's Amyloid β

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two Hepatic Enhancers, HCR.1 and HCR.2, Coordinate the Liver Expression of the Entire Human Apolipoprotein E/C-I/C-IV/C-II Gene Cluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE Synthesis in Human Neuroblastoma Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regionally specific neuronal expression of human APOE gene in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of apolipoprotein and apolipoprotein receptor response to lesion in the rat brain: an in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16687490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5476-05.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16687490%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16687490%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16687490%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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