High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease. (Q46216495)

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7 March 2020

title

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease (English)

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7 March 2020

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9

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7 March 2020

Diego Sepulveda-Falla

2

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7 March 2020

Hermann Altmeppen

4

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7 March 2020

Jakob Matschke

8

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7

Inga Zerr

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7 March 2020

author name string

Frank Dohler

1

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Susanne Krasemann

3

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7 March 2020

Hartmut Schlüter

5

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Diana Hildebrand

6

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language of work or name

English

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publication date

10 February 2014

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7 March 2020

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7 March 2020

volume

137

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7 March 2020

issue

Pt 3

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page(s)

873-886

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Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration.

7 March 2020

cites work

1 reference

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Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein

21 January 2018

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Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

21 January 2018

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gamma-secretases: from cell biology to therapeutic strategies

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

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Prion protein at the crossroads of physiology and disease.

21 January 2018

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Neuropathological stageing of Alzheimer-related changes

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Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues

21 January 2018

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21 January 2018

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Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

21 January 2018

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Association between deposition of beta-amyloid and pathological prion protein in sporadic Creutzfeldt-Jakob disease.

21 January 2018

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Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls

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Consortium to Establish a Registry for Alzheimer's Disease (CERAD): the first twenty years

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An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo

21 January 2018

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Interaction of intracellular beta amyloid peptide with chaperone proteins

21 January 2018

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Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

21 January 2018

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Understanding the natural variability of prion diseases

21 January 2018

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Memory impairment in transgenic Alzheimer mice requires cellular prion protein

21 January 2018

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Human prion diseases: epidemiology and integrated risk assessment

21 January 2018

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The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo

21 January 2018

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α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death

21 January 2018

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Clean Western blot signals from immunoprecipitated samples

21 January 2018

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The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

21 January 2018

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

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Brain amyloid-β oligomers in ageing and Alzheimer's disease

21 January 2018

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Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.

21 January 2018

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21 January 2018

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The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

21 January 2018

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Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1

21 January 2018

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Binding of amyloid beta-protein to intracellular brain proteins in rat and human

21 January 2018

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Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

21 January 2018

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Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

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The P's and Q's of cellular PrP-Aβ interactions

21 January 2018

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The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers

21 January 2018

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Amyloid-β42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWT375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24519981%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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