Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations. (Q46150450)

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20 January 2020

title

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations (English)

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20 January 2020

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1

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20 January 2020

Jean-Christophe Jonas

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20 January 2020

author name string

L Van Lommel

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L Overbergh

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F C Schuit

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publication date

23 January 2009

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20 January 2020

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20 January 2020

volume

52

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issue

3

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20 January 2020

page(s)

463-476

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

20 January 2020

cites work

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12 December 2020

Why expression of some genes is disallowed in beta-cells.

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High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells

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Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells.

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Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets

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MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells

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Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

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Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells.

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Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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Sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction

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Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

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12 December 2020

Critical role for cataplerosis via citrate in glucose-regulated insulin release

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Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

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Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets. A common mechanism for glucose toxicity and lipotoxicity?

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High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB.

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Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells

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Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells

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Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

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Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus

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Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).

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12 December 2020

ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity

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12 December 2020

SREBP1 is required for the induction by glucose of pancreatic beta-cell genes involved in glucose sensing

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12 December 2020

Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species

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12 December 2020

Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells

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12 December 2020

Distinct glucose-dependent stress responses revealed by translational profiling in pancreatic beta-cells.

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12 December 2020

Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal

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12 December 2020

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

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12 December 2020

Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate

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12 December 2020

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

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12 December 2020

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

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12 December 2020

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP.

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12 December 2020

Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells

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12 December 2020

Visualizing superoxide production in normal and diabetic rat islets of Langerhans

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12 December 2020

Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.

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12 December 2020

GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways

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12 December 2020

Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells

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12 December 2020

Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets.

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12 December 2020

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

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12 December 2020

Insulin secretion is highly sensitive to desorption of plasma membrane cholesterol.

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12 December 2020

Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose

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12 December 2020

Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis

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12 December 2020

Culture duration and conditions affect the oscillations of cytoplasmic calcium concentration induced by glucose in mouse pancreatic islets

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12 December 2020

Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity

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12 December 2020

Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress.

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12 December 2020

Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes

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12 December 2020

10.1007/S00125-008-1245-Z

Identifiers

DOI

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20 January 2020

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