Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses. (Q46113876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19234107%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses (English)

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22 January 2020

6

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22 January 2020

author name string

Jin Hyun Kang

1

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22 January 2020

Byung Soo Kim

2

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22 January 2020

Tae Gi Uhm

3

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22 January 2020

Shin-Hwa Lee

4

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22 January 2020

Gap Ryol Lee

5

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22 January 2020

Il Yup Chung

7

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22 January 2020

language of work or name

English

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publication date

20 February 2009

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American Journal of Respiratory and Critical Care Medicine

22 January 2020

published in

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22 January 2020

volume

179

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22 January 2020

issue

10

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22 January 2020

page(s)

875-882

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Asthma: mechanisms of disease persistence and progression

22 January 2020

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Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

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An overview of the Notch signalling pathway

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The many facets of Notch ligands

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HES and HERP families: multiple effectors of the Notch signaling pathway

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Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells

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Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

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Suppression of Th2 cell development by Notch ligands Delta1 and Delta4

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A novel transcription factor, T-bet, directs Th1 lineage commitment

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Notch signaling is an important regulator of type 2 immunity.

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Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling

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TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells

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Notch 1 signaling regulates peripheral T cell activation

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Notch1 augments NF-kappaB activity by facilitating its nuclear retention

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

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Eosinophilic differentiation is promoted by blockage of Notch signaling with a gamma-secretase inhibitor

21 January 2018

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Regulation of functional phenotypes of cord blood derived eosinophils by gamma-secretase inhibitor.

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Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

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L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity

21 January 2018

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Complement activation is critical to airway hyperresponsiveness after acute ozone exposure

21 January 2018

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Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function

21 January 2018

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Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti-Tim-3 antibody in vivo

21 January 2018

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The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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10.1164/RCCM.200806-893OC

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19234107%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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