Strategies to expand transduced hematopoietic stem cells in vivo (Q45874737)

17 December 2017

title

Strategies to expand transduced hematopoietic stem cells in vivo (English)

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17 December 2017

2

Daniela Golinelli

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17 December 2017

Janis L Abkowitz

1

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17 December 2017

Peter Guttorp

series ordinal

3

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17 December 2017

publication date

1 April 2004

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17 December 2017

published in

Molecular Therapy

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17 December 2017

volume

9

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17 December 2017

issue

4

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17 December 2017

page(s)

566-576

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17 December 2017

Side effects of retroviral gene transfer into hematopoietic stem cells

cites work

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Prolonged high-level detection of retrovirally marked hematopoietic cells in nonhuman primates after transduction of CD34+ progenitors using clinically feasible methods

7 January 2021

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Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors

7 January 2021

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Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells

7 January 2021

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Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates.

7 January 2021

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Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with a RD114 pseudotyped oncoretroviral vector.

7 January 2021

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Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.

7 January 2021

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Transient detection of beta-galactosidase activity in hematopoietic cells, following reinjection of retrovirally marked autologous blood progenitors in patients with breast or ovarian cancer receiving high-dose chemotherapy

7 January 2021

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In vivo selection using a cell-growth switch

7 January 2021

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Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

7 January 2021

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Genetic protection of repopulating hematopoietic cells with an improved MDR1-retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice

7 January 2021

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In vivo selection of retrovirally transduced hematopoietic stem cells

7 January 2021

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Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells

7 January 2021

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The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

7 January 2021

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HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation

7 January 2021

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HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

7 January 2021

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Selective expansion of transduced cells for hematopoietic stem cell gene therapy

7 January 2021

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Evidence that hematopoiesis may be a stochastic process in vivo

7 January 2021

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In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

7 January 2021

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Hematopoietic stem cells engraft in mice with absolute efficiency

7 January 2021

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Behavior of hematopoietic stem cells in a large animal

7 January 2021

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Evidence that the number of hematopoietic stem cells per animal is conserved in mammals

7 January 2021

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Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma

7 January 2021

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

7 January 2021

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Report of a second serious adverse event in a clinical trial of gene therapy for X-linked severe combined immune deficiency (X-SCID). Position of the European Society of Gene Therapy (ESGT).

7 January 2021

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Quantitative effects of Nf1 inactivation on in vivo hematopoiesis

7 January 2021

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In vivo expansion of transduced murine hematopoietic cells with a selective amplifier gene

7 January 2021

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Pharmacologically regulated in vivo selection in a large animal

7 January 2021

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In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model.

7 January 2021

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Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model

7 January 2021

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10.1016/J.YMTHE.2004.01.014

7 January 2021

Identifiers

DOI

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17 December 2017

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17 December 2017