High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency (Q45855465)

17 December 2017

title

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency (English)

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17 December 2017

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E Ayuso

1

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F Mingozzi

2

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J Montane

3

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X Leon

4

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X M Anguela

5

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V Haurigot

6

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S A Edmonson

7

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L Africa

8

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S Zhou

9

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K A High

10

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F Bosch

11

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J F Wright

12

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publication date

3 December 2009

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

17

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issue

4

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page(s)

503-510

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Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Purification of recombinant adeno-associated virus type 8 vectors by ion exchange chromatography generates clinical grade vector stock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Serum-free production and column purification of adeno-associated virus type 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

CD8(+) T-cell responses to adeno-associated virus capsid in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Intramuscular administration of AAV1-lipoprotein lipase S447X lowers triglycerides in lipoprotein lipase-deficient patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Effect of gene therapy on visual function in Leber's congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Safety and efficacy of gene transfer for Leber's congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Production and characterization of adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Gene therapy strategies for Duchenne muscular dystrophy utilizing recombinant adeno-associated virus vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Successful treatment of canine hemophilia by continuous expression of canine FVIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Adeno-associated virus vectors can be efficiently produced without helper virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Quantification of adeno-associated virus particles and empty capsids by optical density measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.157

21 January 2018

Identifiers

DOI

10.1038/GT.2009.157

1 reference

17 December 2017

Dimensions Publication ID

1025359547

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17 December 2017