The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. (Q45354108)

13 December 2017

title

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. (English)

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13 December 2017

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14

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13

Thomas Benzing

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13 December 2017

6

Roman-Ulrich Müller

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13 December 2017

Sandra Habbig

1

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13 December 2017

Malte P Bartram

2

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13 December 2017

Josef G Sägmüller

3

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13 December 2017

Anabel Griessmann

4

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13 December 2017

Mareike Franke

5

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13 December 2017

Ricarda Schwarz

7

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13 December 2017

Martin Hoehne

8

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13 December 2017

Carsten Bergmann

9

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13 December 2017

Claudia Tessmer

10

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13 December 2017

H Christian Reinhardt

11

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13 December 2017

Volker Burst

12

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13 December 2017

publication date

1 October 2012

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13 December 2017

published in

Human Molecular Genetics

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13 December 2017

volume

21

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13 December 2017

issue

26

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13 December 2017

page(s)

5528-5538

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Clinical spectrum and pathogenesis of nephronophthisis

13 December 2017

cites work

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Nephronophthisis: disease mechanisms of a ciliopathy

21 January 2018

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Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Hippo signaling in organ size control

21 January 2018

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Coordinating developmental signaling: novel roles for the Hippo pathway.

21 January 2018

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The Hippo Signaling Pathway in Development and Cancer

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Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

21 January 2018

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TAZ is a novel oncogene in non-small cell lung cancer.

21 January 2018

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A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

21 January 2018

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Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

21 January 2018

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TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

21 January 2018

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NEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisis

21 January 2018

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A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

21 January 2018

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Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors.

21 January 2018

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The basal body gene, RPGRIP1L, is a candidate tumour suppressor gene in human hepatocellular carcinoma

21 January 2018

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Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

21 January 2018

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Cystic kidney disease: the role of Wnt signaling

21 January 2018

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The primary cilium: a signalling centre during vertebrate development

21 January 2018

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The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

21 January 2018

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Altered Hippo signalling in polycystic kidney disease.

21 January 2018

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The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling

21 January 2018

1 reference

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Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

The ciliary protein Nek8/Nphp9 acts downstream of Inv/Nphp2 during pronephros morphogenesis and left-right establishment in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS408

Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia

21 January 2018

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Continuous cultures of fused cells secreting antibody of predefined specificity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDS408

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13 December 2017

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