Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice. (Q45296316)

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10 January 2020

title

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice (English)

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10 January 2020

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10 January 2020

Małgorzata Kossut

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10 January 2020

Anthony J Hannan

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10 January 2020

Anita Cybulska-Klosowicz

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Anita Cybulska-Klosowicz

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Colin Blakemore

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Colin Blakemore

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Nektarios K Mazarakis

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Nektarios K Mazarakis

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10 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788762%20AND%20SRC:MED&resulttype=core&format=json

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Anton Van Dellen

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10 January 2020

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Helen Grote

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10 January 2020

language of work or name

English

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publication date

1 March 2005

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10 January 2020

published in

Journal of Neuroscience

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10 January 2020

volume

25

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10 January 2020

issue

12

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10 January 2020

page(s)

3059-3066

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Storage and executive processes in the frontal lobes

10 January 2020

cites work

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Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

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Impaired synaptic plasticity in mice carrying the Huntington's disease mutation

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Longitudinal cognitive and motor changes among presymptomatic Huntington disease gene carriers

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Impaired experience-dependent plasticity in barrel cortex of mice lacking the alpha and delta isoforms of CREB.

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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

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Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

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Experience-dependent plasticity of rat barrel cortex: redistribution of activity across barrel-columns

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Delaying the onset of Huntington's in mice

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Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.

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Timing-based LTP and LTD at vertical inputs to layer II/III pyramidal cells in rat barrel cortex

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Transcriptional dysregulation in Huntington's disease

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Subtle changes among presymptomatic carriers of the Huntington's disease gene

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12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

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Behavioral planning in the prefrontal cortex

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Mice can learn roughness discrimination with vibrissae in a jump stand apparatus

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Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers.

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Neuropsychiatric aspects of Huntington's disease.

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Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression

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Metabolic network abnormalities in early Huntington's disease: an [(18)F]FDG PET study.

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12 December 2020

Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease

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12 December 2020

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

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NMDA receptor function in mouse models of Huntington disease

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Psychiatric symptoms in neurologically asymptomatic Huntington's disease gene carriers: a comparison with gene negative at risk subjects.

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12 December 2020

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

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12 December 2020

Anatomical pathways and molecular mechanisms for plasticity in the barrel cortex.

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Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

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12 December 2020

Long-term depression and long-term potentiation in horizontal connections of the barrel cortex

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12 December 2020

Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.

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12 December 2020

Neocortical long-term potentiation and experience-dependent synaptic plasticity require alpha-calcium/calmodulin-dependent protein kinase II autophosphorylation.

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12 December 2020

Huntington's disease: a synaptopathy?

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12 December 2020

Vibrissal roughness discrimination is barrelcortex-dependent

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12 December 2020

A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease

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12 December 2020

Biometric analyses of vibrissal tactile discrimination in the rat

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12 December 2020

Templates for locating the whisker area in fresh flattened mouse and rat cortex

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12 December 2020

Rats can learn a roughness discrimination using only their vibrissal system.

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12 December 2020

Neuropathological classification of Huntington's disease

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12 December 2020

Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease

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12 December 2020

Cerebral metabolism and atrophy in huntington's disease determined by18FDG and computed tomographic scan

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12 December 2020

Cognitive scores in carriers of Huntington's disease gene compared to noncarriers

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12 December 2020

Partial blocking of NMDA receptors restricts plastic changes in adult mouse barrel cortex

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12 December 2020

Glucose transporter isoform expression in Huntington's disease brain

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12 December 2020

Functional plasticity and neurotransmitter receptor binding in the vibrissal barrel cortex.

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12 December 2020

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

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12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

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12 December 2020

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

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12 December 2020

Short-lasting classical conditioning induces reversible changes of representational maps of vibrissae in mouse SI cortex--a 2DG study.

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12 December 2020

Areal extent quantification of functional representations using intrinsic signal optical imaging

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12 December 2020

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

12 December 2020

Evidence of cortical metabolic dysfunction in early Huntington's disease by single-photon-emission computed tomography

1 reference

12 December 2020

Mechanisms underlying experience-dependent potentiation and depression of vibrissae responses in barrel cortex.

1 reference

12 December 2020

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

12 December 2020

Evidence for specific cognitive deficits in preclinical Huntington's disease.

1 reference

12 December 2020

Calcium/calmodulin-dependent protein kinase II is associated with NR2A/B subunits of NMDA receptor in postsynaptic densities.

1 reference

12 December 2020

Experience-dependent plasticity of adult rat S1 cortex requires local NMDA receptor activation.

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12 December 2020

Cerebral blood flow velocity decreases during cognitive stimulation in Huntington's disease

1 reference

12 December 2020

10.1523/JNEUROSCI.4320-04.2005

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788762%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788762%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

15788762

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