Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase (Q45138630)

9 December 2017

title

Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase (English)

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9 December 2017

Kevin C Qian

1

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9 December 2017

Lian Wang

2

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9 December 2017

Eugene R Hickey

3

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9 December 2017

Joey Studts

4

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9 December 2017

Kevin Barringer

5

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9 December 2017

Charline Peng

6

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9 December 2017

Anthony Kronkaitis

7

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9 December 2017

Jun Li

8

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9 December 2017

Andre White

9

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9 December 2017

Sheenah Mische

10

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9 December 2017

Bennett Farmer

11

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9 December 2017

language of work or name

English

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publication date

3 November 2004

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Journal of Biological Chemistry

9 December 2017

published in

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9 December 2017

volume

280

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9 December 2017

issue

7

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9 December 2017

page(s)

6130-6137

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Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

9 December 2017

cites work

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Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

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Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

21 January 2018

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Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

21 January 2018

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Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway

21 January 2018

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Pim serine/threonine kinases regulate the stability of Socs-1 protein

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The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death

21 January 2018

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Active and inactive protein kinases: structural basis for regulation

21 January 2018

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Autoregulatory mechanisms in protein-tyrosine kinases

21 January 2018

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Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

21 January 2018

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Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product

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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

21 January 2018

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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Identification of the autophosphorylation sites of the Xenopus laevis Pim-1 proto-oncogene-encoded protein kinase.

21 January 2018

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The conformational plasticity of protein kinases

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Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

21 January 2018

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STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

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CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway

21 January 2018

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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

21 January 2018

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Characterization of the regulatory domain of the gamma-subunit of phosphorylase kinase. The two noncontiguous calmodulin-binding subdomains are also autoinhibitory.

21 January 2018

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Protein phosphatase 2A regulates the stability of Pim protein kinases

21 January 2018

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The protein kinase complement of the human genome

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Protein kinase inhibitors: insights into drug design from structure.

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Recent kinase and kinase inhibitor X-ray structures: mechanisms of inhibition and selectivity insights

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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The CCP4 suite: programs for protein crystallography

21 January 2018

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A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Active site-directed protein regulation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409123200

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9 December 2017

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