Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells. (Q45022855)

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English	Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells.	scientific article

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31 December 2019

Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells (English)

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31 December 2019

mitochondrial DNA

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Zofia M Chrzanowska-Lightowlers

5

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31 December 2019

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31 December 2019

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Olga A Kolesnikova

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31 December 2019

Nina S Entelis

2

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31 December 2019

Clarisse Jacquin-Becker

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31 December 2019

Francine Goltzene

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31 December 2019

Robert N Lightowlers

6

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31 December 2019

Robert P Martin

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31 December 2019

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18 August 2004

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31 December 2019

Human Molecular Genetics

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31 December 2019

13

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31 December 2019

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31 December 2019

2519-2534

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31 December 2019

Mitochondria make a come back

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Protein import into mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

RNA delivery into mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Role of an RNA-binding Protein in Import of tRNA into Leishmania Mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Import of RNA into Leishmania mitochondria occurs through direct interaction with membrane-bound receptors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Selective importation of RNA into isolated mitochondria from Leishmania tarentolae

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

"Ping-pong" interactions between mitochondrial tRNA import receptors within a multiprotein complex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

A nuclear encoded and mitochondrial imported dicistronic tRNA precursor in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

In vivo import of unspliced tRNATyr containing synthetic introns of variable length into mitochondria of Leishmania tarentolae

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

In Vitro Import of a Nuclearly Encoded tRNA into Mitochondria of Solanum tuberosum

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

The anticodon and the D-domain sequences are essential determinants for plant cytosolic tRNA(Val) import into mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

An intact protein translocating machinery is required for mitochondrial import of a yeast cytoplasmic tRNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

tRNAs and proteins are imported into mitochondria of Trypanosoma brucei by two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Import of nuclear deoxyribonucleic acid coded lysine-accepting transfer ribonucleic acid (anticodon C-U-U) into yeast mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Evidence for the presence of 5S rRNA in mammalian mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Structural requirements of tRNALys for its import into yeast mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Mitochondrial tRNA import: are there distinct mechanisms?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Mitochondrial diseases in man and mouse

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Molecular genetic aspects of human mitochondrial disorders

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

The mitochondrial DNA transfer RNA(Lys)A-->G(8344) mutation and the syndrome of myoclonic epilepsy with ragged red fibres (MERRF). Relationship of clinical phenotype to proportion of mutant mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNA(Lys) with the MERRF encephalomyopathy pathogenic mutation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Comparison of the RNA polymerase III transcription machinery in Schizosaccharomyces pombe, Saccharomyces cerevisiae and human

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Survey and summary: transcription by RNA polymerases I and III.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

In vitro analysis of mutations causing myoclonus epilepsy with ragged-red fibers in the mitochondrial tRNA(Lys)gene: two genotypes produce similar phenotypes.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

RNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Fractionation of mitochondrial RNA from HeLa cells by high-resolution electrophoresis under strongly denaturing conditions

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Evidence for import of a lysyl-tRNA into marsupial mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

A roundabout route to gene therapy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Isolation and subfractionation of mitochondria from animal cells and tissue culture lines

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

5 S rRNA and tRNA import into human mitochondria. Comparison of in vitro requirements

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDH267

21 January 2018

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