Black mamba venom peptides target acid-sensing ion channels to abolish pain (Q44940323)

7 December 2017

title

Black mamba venom peptides target acid-sensing ion channels to abolish pain (English)

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envenomation resulting in negative regulation of sensory perception of pain in other organism

7 December 2017

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envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism

GO:0044741

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envenomation resulting in modulation of acid-sensing ion channel activity in other organism

GO:0044735

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envenomation resulting in modulation of sensory perception of pain in other organism

GO:0044733

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envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism

GO:0044742

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Miguel Salinas

3

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Eric Lingueglia

object named as

Eric Lingueglia

11

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author name string

Sylvie Diochot

1

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7 December 2017

Anne Baron

2

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7 December 2017

Dominique Douguet

4

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7 December 2017

Sabine Scarzello

5

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7 December 2017

Anne-Sophie Dabert-Gay

6

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7 December 2017

Delphine Debayle

7

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7 December 2017

Valérie Friend

8

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7 December 2017

Abdelkrim Alloui

9

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7 December 2017

Michel Lazdunski

10

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7 December 2017

language of work or name

English

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publication date

3 October 2012

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7 December 2017

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7 December 2017

volume

490

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7 December 2017

issue

7421

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7 December 2017

page(s)

552-555

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Therapeutic potential of venom peptides

7 December 2017

cites work

1 reference

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Conus venoms: a rich source of novel ion channel-targeted peptides

21 January 2018

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Acid-sensing ion channels in postoperative pain

21 January 2018

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ASIC3, a sensor of acidic and primary inflammatory pain

21 January 2018

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A tarantula peptide against pain via ASIC1a channels and opioid mechanisms

21 January 2018

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Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia

21 January 2018

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Ziconotide for treatment of severe chronic pain

21 January 2018

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Effect of continuous intrathecal infusion of omega-conopeptides, N-type calcium-channel blockers, on behavior and antinociception in the formalin and hot-plate tests in rats

21 January 2018

1 reference

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Acid-sensing ion channels (ASICs): pharmacology and implication in pain

21 January 2018

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Acid-induced pain and its modulation in humans.

21 January 2018

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A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

21 January 2018

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Structure, function and evolution of three-finger toxins: mini proteins with multiple targets

21 January 2018

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A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons

21 January 2018

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Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.

21 January 2018

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Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons

21 January 2018

1 reference

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Acid sensing ion channels in dorsal spinal cord neurons

21 January 2018

1 reference

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A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells

21 January 2018

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A proton-gated cation channel involved in acid-sensing

21 January 2018

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A sensory neuron-specific, proton-gated ion channel

21 January 2018

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Snake venom alpha-neurotoxins and other 'three-finger' proteins

21 January 2018

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ASIC-like, proton-activated currents in rat hippocampal neurons

21 January 2018

1 reference

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Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

21 January 2018

1 reference

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Molecular and functional characterization of acid-sensing ion channel (ASIC) 1b

21 January 2018

1 reference

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Cellular and Molecular Mechanisms of Pain

21 January 2018

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Overcoming obstacles to developing new analgesics

21 January 2018

1 reference

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The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

21 January 2018

1 reference

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Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

21 January 2018

1 reference

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Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

21 January 2018

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Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom

21 January 2018

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Unmasking venom gland transcriptomes in reptile venoms

21 January 2018

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Accelerated evolution in the protein-coding regions is universal in crotalinae snake venom gland phospholipase A2 isozyme genes

21 January 2018

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Easier threading through web-based comparisons and cross-validations.

21 January 2018

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Protein homology detection by HMM-HMM comparison

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Incremental threading optimization (TITO) to help alignment and modelling of remote homologues.

21 January 2018

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MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

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Electrostatics of nanosystems: application to microtubules and the ribosome

21 January 2018

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An electrophysiological characterisation of long-term potentiation in cultured dissociated hippocampal neurones

21 January 2018

1 reference

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Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23034652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23034652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11494

1 reference

Dimensions Publication ID

7 December 2017

1033270170

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