FLT3 receptors with internal tandem duplications promote cell viability and proliferation by signaling through Foxo proteins (Q44775125)

6 December 2017

title

FLT3 receptors with internal tandem duplications promote cell viability and proliferation by signaling through Foxo proteins (English)

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6 December 2017

Blanca Scheijen

1

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6 December 2017

Hai T Ngo

series ordinal

2

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6 December 2017

Hyun Kang

series ordinal

3

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6 December 2017

James D Griffin

series ordinal

4

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6 December 2017

language of work or name

English

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publication date

1 April 2004

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6 December 2017

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6 December 2017

volume

23

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6 December 2017

issue

19

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6 December 2017

page(s)

3338-3349

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Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

6 December 2017

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

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Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes. Regulation of cell cycling as a downstream molecule of thrombopoietin signaling

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Negative regulation of the forkhead transcription factor FKHR by Akt.

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Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

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Forkhead transcription factors contribute to execution of the mitotic programme in mammals

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7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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7 January 2021

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

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7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

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7 January 2021

TEL/platelet-derived growth factor receptor beta activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle

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7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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7 January 2021

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

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7 January 2021

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7 January 2021

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7 January 2021

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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7 January 2021

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

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7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

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7 January 2021

A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo

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7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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7 January 2021

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

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7 January 2021

Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia

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7 January 2021

Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt.

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7 January 2021

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

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7 January 2021

Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease

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7 January 2021

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia

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7 January 2021

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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7 January 2021

Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors

1 reference

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7 January 2021

Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival

1 reference

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7 January 2021

Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

1 reference

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7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

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7 January 2021

BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207456

7 January 2021

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207456

7 January 2021

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

1 reference

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7 January 2021

Targeted inhibition of FLT3 overcomes the block to myeloid differentiation in 32Dcl3 cells caused by expression of FLT3/ITD mutations

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207456

1 reference

6 December 2017

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