Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. (Q44519392)

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6 November 2019

title

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis (English)

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X-ray scattering technique

6 November 2019

main subject

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10

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Paul Mould

1

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6 November 2019

author name string

Emlyn J H Symonds

2

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Patrick A Buckley

3

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J Günter Grossmann

4

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6 November 2019

Paul A McEwan

5

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Stephanie J Barton

6

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6 November 2019

Janet A Askari

7

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Susan E Craig

8

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Jordi Bella

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language of work or name

English

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publication date

19 July 2003

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Journal of Biological Chemistry

6 November 2019

published in

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volume

278

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issue

41

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page(s)

39993-39999

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In vivo functions of integrins: lessons from null mutations in mice

6 November 2019

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Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

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Integrin activation takes shape

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Integrin activation and structural rearrangement

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Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

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Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

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Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.

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Generation of a minimal alpha5beta1 integrin-Fc fragment

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The N-terminal extension of rusticyanin is not responsible for its acid stability

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Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein

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Determination of domain structure of proteins from X-ray solution scattering

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Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain

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Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor

21 January 2018

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Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure

21 January 2018

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Advances in structure analysis using small-angle scattering in solution

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Low resolution meets high: towards a resolution continuum from cells to atoms

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Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

21 January 2018

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A minimized human integrin alpha(5)beta(1) that retains ligand recognition

21 January 2018

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Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

21 January 2018

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2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region

21 January 2018

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21 January 2018

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Identifiers

DOI

10.1074/JBC.M304627200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference