Lens fibers have a fully functional ubiquitin-proteasome pathway (Q44404925)

2 December 2017

title

Lens fibers have a fully functional ubiquitin-proteasome pathway (English)

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ubiquitin-proteasome system

2 December 2017

main subject

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author

Paulo Pereira

1

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2 December 2017

Fu Shang

2

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2 December 2017

Marisa Hobbs

3

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2 December 2017

Henrique Girão

4

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2 December 2017

Allen Taylor

5

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2 December 2017

publication date

1 May 2003

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Experimental Eye Research

2 December 2017

published in

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2 December 2017

volume

76

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2 December 2017

issue

5

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2 December 2017

page(s)

623-631

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The Proteasome: Paradigm of a Self-Compartmentalizing Protease

2 December 2017

cites work

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Evidence that fibroblast growth factor promotes lens fibre differentiation

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Molecular Evidence for the Involvement of Alpha Crystallin in the Colouration/Crosslinking of Crystallins in Age-related Nuclear Cataract

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Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells

7 January 2021

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Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7.

7 January 2021

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The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage

7 January 2021

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7 January 2021

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Bovine lens epithelial cells have a ubiquitin-dependent proteolysis system

7 January 2021

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Degradation of differentially oxidized alpha-crystallins in bovine lens epithelial cells

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Identification of a family of closely related human ubiquitin conjugating enzymes

7 January 2021

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The ultrastructure of epithelial and fiber cells in the crystalline lens.

7 January 2021

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A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

7 January 2021

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Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

7 January 2021

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An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele

7 January 2021

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The photoreceptor G-protein transducin (Gt) is a substrate for ubiquitin-dependent proteolysis

7 January 2021

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Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

7 January 2021

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Activation of a UBC4-dependent pathway of ubiquitin conjugation during postnatal development of the rat testis

7 January 2021

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Ubiquitin-activating enzyme (E1) isoforms in lens epithelial cells: origin of translation, E2 specificity and cellular localization determined with novel site-specific antibodies

7 January 2021

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Ubiquitin-dependent pathway is up-regulated in differentiating lens cells

7 January 2021

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7 January 2021

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Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated

7 January 2021

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Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway

7 January 2021

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Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells

7 January 2021

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Deamidation of Asn-143 of gamma S crystallin from protein aggregates of the human lens

7 January 2021

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The 26S proteasome: subunits and functions

7 January 2021

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Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

7 January 2021

1 reference

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A novel rat homolog of the Saccharomyces cerevisiae ubiquitin-conjugating enzymes UBC4 and UBC5 with distinct biochemical features is induced during spermatogenesis

7 January 2021

1 reference

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Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis

7 January 2021

1 reference

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10.1016/S0014-4835(03)00020-4

7 January 2021

Identifiers

DOI

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2 December 2017

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