Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block. (Q44072116)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

transmembrane protein

0 references

0 references

Vladimir Yarov-Yarovoy

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Jancy C McPhee

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Diane Idsvoog

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Caroline Pate

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Todd Scheuer

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

William A Catterall

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

language of work or name

0 references

publication date

18 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

277

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

38

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

35393-35401

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structure and function of voltage‐gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Sodium channels and gating currents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular model of the action potential sodium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular basis of charge movement in voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Inhibition of inactivation of single sodium channels by a site-directed antibody

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A mutation in segment IVS6 disrupts fast inactivation of sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Interaction between the sodium channel inactivation linker and domain III S4-S5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Role in fast inactivation of the IV/S4–S5 loop of the human muscle Na+ channel probed by cysteine mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Inactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Glutamine substitution at alanine1649 in the S4-S5 cytoplasmic loop of domain 4 removes the voltage sensitivity of fast inactivation in the human heart sodium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A unique role for the S4 segment of domain 4 in the inactivation of sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Nomenclature of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated μ1 Na + channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Local anesthetic block of batrachotoxin-resistant muscle Na+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Multiple sequence alignment with Clustal X

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

The anatomy and taxonomy of protein structure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structural basis of amino acid alpha helix propensity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

State-dependent inhibition of Na+ currents by the neuroprotective agent 619C89 in rat hippocampal neurons and in a mammalian cell line expressing rat brain type IIA Na+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Electrophysiology of sipatrigine: a lamotrigine derivative exhibiting neuroprotective effects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

A mutation in segment I-S6 alters slow inactivation of sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

The open pore conformation of potassium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structural rearrangements underlying K+-channel activation gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structure of the KcsA channel intracellular gate in the open state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Inactivation of the sodium channel. II. Gating current experiments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Conformational pathways in the gating of Escherichia coli mechanosensitive channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Structural parts involved in activation and inactivation of the sodium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206126200

21 January 2018

Identifiers

10.1074/JBC.M206126200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

release_vu6gzyfdfvgg3hxprtnvgl6h5m

1 reference

https://api.fatcat.wiki/v0/release/vu6gzyfdfvgg3hxprtnvgl6h5m

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12130650%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44072116&oldid=2106270926"