Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases (Q43943330)

28 November 2017

title

Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases (English)

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28 November 2017

author name string

Jaroslaw Dziegielewski

series ordinal

1

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28 November 2017

Terry A Beerman

series ordinal

2

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28 November 2017

language of work or name

English

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publication date

1 April 2002

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Journal of Biological Chemistry

28 November 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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28 November 2017

volume

277

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28 November 2017

issue

23

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28 November 2017

page(s)

20549-20554

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The DNA damage response: putting checkpoints in perspective

28 November 2017

cites work

1 reference

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A role for ATR in the DNA damage-induced phosphorylation of p53

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DNA-dependent protein kinase

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Substrate specificities and identification of putative substrates of ATM kinase family members

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

21 January 2018

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The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

21 January 2018

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Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

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Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

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Structure of DNA-dependent protein kinase: implications for its regulation by DNA.

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DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

21 January 2018

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

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DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes

21 January 2018

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Mode of action of C-1027, a new macromolecular antitumor antibiotic with highly potent cytotoxicity, on human hepatoma BEL-7402 cells

21 January 2018

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Effects of the DNA-damaging enediyne C-1027 on intracellular SV40 and genomic DNA in green monkey kidney BSC-1 cells

21 January 2018

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21 January 2018

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DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

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21 January 2018

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Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin

21 January 2018

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Kinetics of cleavage of intra- and extracellular simian virus 40 DNA with the enediyne anticancer drug C-1027.

21 January 2018

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21 January 2018

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Condensed tannins induce micronuclei in cultured V79 Chinese hamster cells

21 January 2018

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The cellular response to DNA damage induced by the enediynes C-1027 and neocarzinostatin includes hyperphosphorylation and increased nuclear retention of replication protein a (RPA) and trans inhibition of DNA replication

21 January 2018

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Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA

21 January 2018

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Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner

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21 January 2018

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C1027 chromophore, a potent new enediyne antitumor antibiotic, induces sequence-specific double-strand DNA cleavage

21 January 2018

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Clustered damages and total lesions induced in DNA by ionizing radiation: oxidized bases and strand breaks

21 January 2018

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Some characteristics of DNA strand scission by macromolecular antitumor antibiotic C-1027 containing a novel enediyne chromophore

21 January 2018

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Assessment of preferential cleavage of an actively transcribed retroviral hybrid gene in murine cells by deoxyribonuclease I, bleomycin, neocarzinostatin, or ionizing radiation

21 January 2018

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Mechanism of Formation of Novel Covalent Drug·DNA Interstrand Cross-Links and Monoadducts by Enediyne Antitumor Antibiotics

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109897200

1 reference

release_kgkit6t46re3rdzcnd7sfpdefa

28 November 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/kgkit6t46re3rdzcnd7sfpdefa

mapped directly with Wikidata item

24 November 2022

based on heuristic

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