ER aminopeptidases generate a unique pool of peptides for MHC class I molecules. (Q43655803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11429550%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11429550%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author

Stephanie Valderramos

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11429550%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

Serwold T

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11429550%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Shastri N

series ordinal

3

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9 November 2019

language of work or name

English

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publication date

1 July 2001

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9 November 2019

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9 November 2019

volume

2

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9 November 2019

issue

7

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9 November 2019

page(s)

644-651

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

9 November 2019

cites work

1 reference

7 January 2021

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

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Mechanisms of MHC class I--restricted antigen processing

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Discrete proteolytic intermediates in the MHC class I antigen processing pathway and MHC I-dependent peptide trimming in the ER.

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Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

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The major substrates for TAP in vivo are derived from newly synthesized proteins

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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Ham-2 corrects the class I antigen-processing defect in RMA-S cells

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TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

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How selective is the transporter associated with antigen processing?

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Murine Transporter Associated with Antigen Presentation (TAP) Preferences Influence Class I–restricted T Cell Responses

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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

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Trimming of antigenic peptides in an early secretory compartment

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Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum

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The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER

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Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing

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Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

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Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis

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Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

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Herpes simplex virus turns off the TAP to evade host immunity

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The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma.

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Proline residues in the maturation and degradation of peptide hormones and neuropeptides

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Proline-dependent structural and biological properties of peptides and proteins

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Overlap in the repertoires of peptides bound in vivo by a group of related class I HLA-B allotypes

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The peptide-binding motif for the human transporter associated with antigen processing

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Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

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Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

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Cellular peptide composition governed by major histocompatibility complex class I molecules.

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Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex

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Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

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Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

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Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens

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A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells

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Distinguishing self from nonself: immunogenicity of the murine H47 locus is determined by a single amino acid substitution in an unusual peptide

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7 January 2021

Minors Held by Majors: The H13 Minor Histocompatibility Locus Defined as a Peptide/MHC Class I Complex

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Major histocompatibility class I molecules can present cryptic translation products to T-cells

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Preparation of microsomal membranes for cotranslational protein translocation

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